Evidence map›Paper›PMID 34316626›Full record

ArticleClinical parkinsonism & related disorders2020

Tremorography in fragile X-associated tremor/ataxia syndrome, Parkinson's disease and essential tremor.

Erin E Robertson, Deborah A Hall, Gian Pal, Bichun Ouyang, Yuanqing Liu, Jessica M Joyce, Elizabeth Berry-Kravis, Joan A O'Keefe

Open access · goldAbstract read
In one paragraph

Article in Clinical parkinsonism & related disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Essential tremor-like phenotype in Fragile X carrier women.Clinical parkinsonism & related disorders · 2026
    Article
  4. Article
  5. Article
  6. Prodromal Markers of Upper Limb Deficits inMovement disorders clinical practice · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Erin E RobertsonDepartment of Cell and Molecular Medicine, Rush University Medical Center, Chicago, IL, United States of America.
Deborah A HallDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, United States of America.
Gian PalDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, United States of America.
Bichun OuyangDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, United States of America.
Yuanqing LiuDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, United States of America.
Jessica M JoyceDepartment of Cell and Molecular Medicine, Rush University Medical Center, Chicago, IL, United States of America.
Elizabeth Berry-KravisDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, United States of America.
Joan A O'KeefeDepartment of Cell and Molecular Medicine, Rush University Medical Center, Chicago, IL, United States of America.
Rush University Medical Center · US

Funding

Impact of Cognitive function on Balance and Gait Markers for FXTASK01HD088762 · NICHD · RUSH UNIVERSITY MEDICAL CENTER · PI O'KEEFE, JOAN A · 2016 to 2021
$711k
NICHD NIH HHS K01 HD088762
6 · The paper itself

Abstract

backgroundFragile X-associated tremor/ataxia syndrome (FXTAS), a neurodegenerative disease affecting carriers of a 55-200 CGG repeat in the

methodsThe inertial sensor based Kinesia

resultsFXTAS participants had reduced finger tap speed compared to those with ET, and ET had increased kinetic tremor compared to PD. Higher kinetic tremor distinguished FXTAS from PD (

conclusionsThis is the first quantitative study to compare tremor and bradykinesia in FXTAS, PD and ET. Kinetic tremor and bradykinesia measures using a quantitative inertial sensor system distinguished FXTAS from PD and ET, respectively. Such technologies may be useful for detecting precise tremor and bradykinesia abnormalities and distinguishing the tremor and bradykinesia profiles in each of these disorders.

Indexed as

bradykinesiaessential tremor (ET)Fragile X-associated tremor/ataxia syndrome (FXTAS)Parkinson's disease (PD)tremortremorography

Identifiers

PMID34316626
PMCPMC8298795
OpenAlexW3001401427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.