ArticlePediatric gastroenterology, hepatology & nutrition2021
Growth in Infants with Cow's Milk Protein Allergy Fed an Amino Acid-Based Formula.
Article in Pediatric gastroenterology, hepatology & nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The trial behind it
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Metagenomic Analysis Reveals Alterations in the Gut Microbiome of Preterm Infants with Extrauterine Growth Restriction.Current microbiology · 2026Article
- Growth in healthy infants with cow's milk protein allergy fed extensively hydrolyzed or amino acid-based formulas.BMC nutrition · 2024Article
- Growth and Nutritional Biomarkers in Brazilian Infants with Cow's Milk Allergy at Diagnosis and 18-Month Follow-Up: A Prospective Cohort Study.Pediatric gastroenterology, hepatology & nutrition · 2023Article
- Nutritional Strategies for the Prevention and Management of Cow's Milk Allergy in the Pediatric Age.Nutrients · 2023Review
- Evolution of nutritional status and associated factors among formula-fed infants with cow's milk protein allergy in a government program.Archives of public health = Archives belges de sante publique · 2023Article
- Article
- Alternatives to Cow's Milk-Based Infant Formulas in the Prevention and Management of Cow's Milk Allergy.Foods (Basel, Switzerland) · 2022Review
- Article
- Current Guidelines and Future Strategies for the Management of Cow's Milk Allergy.Journal of asthma and allergy · 2021Review
Corrections and comments
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Authors and funding
13 authors at 11 institutions in 10 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present study assessed the role of an amino acid-based formula (AAF) in the growth of infants with cow's milk protein allergy (CMPA).
methodsNon-breastfed, term infants aged 0-6 months with symptoms suggestive of CMPA were recruited from 10 pediatric centers in China. After enrollment, infants were started on AAF for two weeks, followed by an open food challenge (OFC) with cow's milk-based formula (CMF). Infants with confirmed CMPA remained on AAF until 9 months of age, in conjunction with a cow's milk protein-free complementary diet. Body weight, length, and head circumference were measured at enrollment and 9 months of age. Measurements were converted to weight-for-age, length-for-age, and head circumference-for-age Z scores (WAZ, LAZ, HCAZ), based on the World Health Organization growth reference.
resultsOf 254 infants (median age 16.1 weeks, 50.9% male), 218 (85.8%) were diagnosed with non-IgE-mediated CMPA, 33 (13.0%) tolerated CMF, and 3 (1.2%) did not complete the OFC. The mean WAZ decreased from 0.119 to -0.029 between birth and enrollment (
conclusionThe amino acid-based study formula, in conjunction with a cow's milk protein-free complementary diet, supported normal growth till 9 months of age in a cohort of Chinese infants with challenge-confirmed non-IgE-mediated CMPA.
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