Evidence map›Paper›PMID 34316472›Full record

ArticlePediatric gastroenterology, hepatology & nutrition2021

Effector Memory CD8

Da-Hee Yang, Hyunju Lee, Naeun Lee, Min Sun Shin, Insoo Kang, Ki-Soo Kang

Open access · diamondAbstract read
In one paragraph

Article in Pediatric gastroenterology, hepatology & nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Expression of IL-7RαPediatric gastroenterology, hepatology & nutrition · 2024
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Da-Hee YangGraduate School, Jeju National University, Jeju, Korea.ORCID https://orcid.org/0000-0001-8631-1720
Hyunju LeeDepartment of Pediatrics, Jeju National University Hospital, Jeju, Korea.ORCID https://orcid.org/0000-0003-0457-635X
Naeun LeeCenter for Integrative Rheumatoid Transcriptomics and Dynamics, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-1254-6866
Min Sun ShinDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.ORCID https://orcid.org/0000-0003-2516-9251
Insoo KangDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.ORCID https://orcid.org/0000-0001-7483-1171
Ki-Soo KangDepartment of Pediatrics, Jeju National University Hospital, Jeju, Korea.ORCID https://orcid.org/0000-0001-6374-8356
Jeju National University Hospital · KRYale University · USCatholic University of Korea · KRJeju National University · KR

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

purposeWe investigated the association of effector memory (EM) CD8

methodsSurface and intracellular staining of peripheral blood mononuclear cells was performed. Anti-interleukin-7 receptor-alpha (IL-7Rα) and CX3CR1 antibodies were used to stain the subsets of EM CD8

resultsOf the 47 obese children, 11 were female. Children with MS had significantly higher levels of serum insulin (34.8±13.8 vs. 16.4±6.3 μU/mL,

conclusionIn obese children with MS, the changes in immunity due to changes in EM CD8

Indexed as

CD4CD8ChildHypertriglyceridemiaMetabolic syndromeObesityT-Lymphocytes

Identifiers

PMID34316472
PMCPMC8279823
OpenAlexW3180930677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.