ArticlePlastic and reconstructive surgery. Global open2021
Implant Loss and Associated Risk Factors following Implant-based Breast Reconstructions.
Article in Plastic and reconstructive surgery. Global open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Nipple or skin-sparing mastectomy flap: can preoperative breast-MRI predict post-operative complications?Updates in surgery · 2026Article
- Effectiveness of the Implementation of a Bundle Protocol for the Reduction of Postmastectomy Reconstruction Failures.Plastic and reconstructive surgery. Global open · 2026Article
- A Brand-New Drainage Fluid Predictor, ICAM-1 for Implant Loss After the Immediate Reconstruction of Breast.Breast cancer (Dove Medical Press) · 2026Article
- Short-Term Outcomes of Post-Mastectomy Immediate Pre-Pectoral Reconstruction with Implant and Acellular Dermal Matrix.Journal of clinical medicine · 2025Article
- Pilot Study: Blue Light Photobiomodulation for the Treatment of Complicated Wounds in Breast Surgery.Plastic and reconstructive surgery. Global open · 2025Article
- Two-stage Implant-based Breast Reconstruction Without the Use of Tissue Expanders.Plastic and reconstructive surgery. Global open · 2025Article
- Factors Affecting Implant Salvage in Patients with Complications After Post-Mastectomy Implant-Based Reconstruction.Journal of clinical medicine · 2025Article
- Reconstructing Failure: Assessing Surgical and Patient-Reported Outcomes after Loss of Initial Breast Reconstruction.Plastic and reconstructive surgery · 2025Article
- A Novel Fat-Augmented Omentum-Based Construct Is a Cost-Effective Alternative for Autologous Breast Reconstruction.Journal of clinical medicine · 2025Article
- Polypropylene Mesh in Nipple-Sparing Mastectomy and Immediate Implant-based Breast Reconstruction in Vietnamese Early Breast Cancer Patients: Safe and Feasible.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Recognizing and Managing Breast Implant Complications: A Review for Healthcare Providers Who Treat Women Who Underwent Breast Implant-Based Surgery.International journal of women's health · 2025Review
- Methods in regression analysis in surgical oncology research-best practice guidelines.Journal of surgical oncology · 2024Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Implant loss is the most severe complication of implant-based breast reconstructions. This study aimed to evaluate the incidence of implant loss and other complications, identify associated risk factors, and create a risk model for implant loss.
methodsThis was a retrospective cohort study of all patients who underwent a mastectomy, followed by either a two-stage or a direct-to-implant breast reconstruction. Patient variables, operative characteristics, and postoperative complications were obtained from the patient records. A multivariate mixed-effects logistic regression model was used to create a risk model for implant loss.
resultsA total of 297 implant-based breast reconstructions were evaluated. Overall, the incidence of implant loss was 11.8%. Six risk factors were significantly associated with implant loss: obesity, a bra cup size larger than C, active smoking status, a nipple-preserving procedure, a direct-to-implant reconstruction, and a lower surgeon's volume. A risk model for implant loss was created, showing a predicted risk of 8.4%-13% in the presence of one risk factor, 21.9%-32.5% in the presence of two, 47.5%-59.3% in the presence of three, and over 78.2% in the presence of four risk factors.
conclusionsThe incidence of implant loss in this study was 11.8%. Six associated significant risk factors were identified. Our risk model for implant loss revealed that the predicted risk increased over 78.2% when four risk factors were present. This risk model can be used to better inform patients and decrease the risk of implant loss by optimizing surgery using personalized therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.