Evidence map›Paper›PMID 34316229›Full record

ArticleJournal of human reproductive sciences

Reduced Angiopoietin-2 as a Predictive Biomarker for Clomiphene Citrate Resistance in Polycystic Ovary Syndrome.

Luxmipratha Rajendiran, Hanumanthappa Nandeesha, Thyagaraju Chitra

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Luxmipratha RajendiranDepartment of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Hanumanthappa NandeeshaDepartment of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Thyagaraju ChitraDepartment of Obstetrics and Gynecology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Jawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEven though angiopoeitin-2 and interleukin (IL)-23 are known to be altered in polycystic ovary syndrome (PCOS), their association with clomiphene citrate (CC) resistance has not been studied.

aimThe objective of the study was to investigate whether angiopoietin-2 levels are associated with inflammation and CC resistance in PCOS. SETTINGS AND

designThis study was conducted in a tertiary care hospital. MATERIALS AND

methodsEighty-one women diagnosed with PCOS and on treatment with CC were enrolled in the study. Angiopoeitin-2 and IL -23 were analyzed in all the subjects.

resultsAngiopoietin-2 was significantly reduced (

conclusionWe conclude that reduced angiopoietin-2 levels predict CC resistance in women with PCOS.

Indexed as

Angiopoietinsclomiphene citrateinterleukinspolycystic ovary syndrome

Identifiers

PMID34316229
PMCPMC8279058
OpenAlexW3176673005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.