Evidence map›Paper›PMID 34316226›Full record

ArticleJournal of human reproductive sciences

Hydrogen Peroxide Has Adverse Effects on Human Sperm Quality Parameters, Induces Apoptosis, and Reduces Survival.

Dwi Ari Pujianto, Mona Oktarina, Ida Ayu Sharma Sharaswati, Yulhasri

Open access · diamondAbstract read
In one paragraph

Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Can the Quality of Semen Affect the Fertilisation Indices of Turkey Eggs?International journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. Frontiers in veterinary science · 2025
    Article
  10. The association of spermInternational journal of reproductive biomedicine · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The Impact ofTheScientificWorldJournal · 2023
    Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dwi Ari PujiantoDepartment of Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Mona OktarinaMaster Program for Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Ida Ayu Sharma SharaswatiMaster Program for Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
YulhasriDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
University of Indonesia · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne of the causes of male fertility disorders is the exposure of oxidative stress on the human sperm. Understanding the mechanism of disturbance is important to develop a better treatment for infertile or subfertile patients.

aimsThe aim of this study was to analyze the effects of hydrogen peroxide (H SETTINGS AND

designThis study used an experimental design. MATERIALS AND

methodsSperm cells from 15 donors were washed in a Percoll gradient and dissolved in Biggers, Whitter, and Whittingham medium. Cells were incubated with H STATISTICAL ANALYSIS USED: One-way ANOVA on SPSS 21 combined with

resultsSperm viability and kinetic were significantly reduced at H

conclusionsH

Indexed as

AKTcapacitationcaspasehydrogen peroxidesperm

Identifiers

PMID34316226
PMCPMC8279063
OpenAlexW3173519756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.