ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2021
Association between Urinary Potassium Excretion and Acute Kidney Injury in Critically Ill Patients.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 9 citations in OpenAlex.
- Kidneys on the Frontline: Nephrologists Tackling the Wilds of Acute Kidney Injury in Trauma Patients-From Pathophysiology to Early Biomarkers.Diagnostics (Basel, Switzerland) · 2025Review
- Introducing the "urine biochemical approach": an alternative tool for improving acute kidney injury monitoring in critically ill patients.Frontiers in nephrology · 2025Article
- Low urinary sodium-to-potassium ratio in the early phase following single-unit cord blood transplantation is a predictive factor for poor non-relapse mortality in adults.Scientific reports · 2024Article
- Urine biochemistry assessment in the sequential evaluation of renal function: Time to think outside the box.Frontiers in medicine · 2022Article
- Acute Kidney Injury in the Intensive Care Unit: The Most Reliable Way to Predict the Future is to Create It.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
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6 authors at 1 institution in 1 country.
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Abstract
introductionAcute kidney injury (AKI) is defined in terms of serum creatinine (SrCrt) and urine output (UO). AKI occurs in 25% of critically ill patients, which increases the risk of morbidity and mortality. Early diagnosis of AKI is challenging, as utility of biomarkers is limited. This study is the first of its kind to estimate urinary potassium (UrK) excretion and its association with AKI in an Indian intensive care unit (ICU). AIMS AND
objectivesTo study the association between UrK excretion and its ability to predict AKI in ICU patients. MATERIAL AND
methodsDuring this prospective observational study, the patient's urinary indices and renal function tests were measured on day 1 of the ICU admission. UrK excretion and creatinine clearance (CrCl) were calculated from a 2-hour morning urine sample. Association between 2-hour UrK excretion and calculated CrCl and their ability to predict AKI in the subsequent 7 days was evaluated by Kidney Disease Improving Global Outcome (KDIGO)-AKI grading.
resultsHundred patients admitted to ICU with a mean age of 53.59 ± 15.8 years were studied. The mean UrK excretion of 4.39 ± 2.52 was correlated linearly with CrCl and has a better prediction to AKI with the area under the receiver-operating characteristic curve value of 0.809 (CI 0.719-0.899), with a significant
conclusionDiagnosis of AKI with traditional methods is not promising. UrK excretion correlates well with CrCl, which can be considered as the simplest accessible marker for predicting AKI in ICUs. HOW TO CITE THIS ARTICLE: Kumar NS, Kumar GN, Misra KC, Rao M, Chitithoti S, Prakash SY
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