Evidence map›Paper›PMID 34316140›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2021

Clinicoepidemiological Features and Mortality Analysis of Deceased Patients with COVID-19 in a Tertiary Care Center.

Richa Aggarwal, Ridhima Bhatia, Kshitija Kulshrestha, Kapil D Soni, Renjith Viswanath, Ashutosh K Singh, Karthik V Iyer, Puneet Khanna, Sulagna Bhattacharjee, Nishant Patel and 16 more

Abstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Six-month Morbidity and Mortality in Patients after Recovery from COVID-19.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
  6. Determinants of death in critically ill COVID-19 patients during the first wave of COVID-19: a multicenter study in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Observational
  7. Reanalyzing the Mortality Analysis of COVID-19 Deaths in a Tertiary Care Center in India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Article
  8. COVID-19: Epidemiology, Case Fatalities and the Adversaries within.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Richa AggarwalCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-4531-2759
Ridhima BhatiaDepartment of Anaesthesiology, Pain Medicine and Critical Care, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-0084-1948
Kshitija KulshresthaCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-9652-142X
Kapil D SoniDepartment of Anaesthesiology, Pain Medicine and Critical Care, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0003-1214-4119
Renjith ViswanathDepartment of Anaesthesiology, Pain Medicine and Critical Care, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0003-4198-4256
Ashutosh K SinghDepartment of Pulmonary and Sleep Medicine, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-4421-8090
Karthik V IyerDepartment of Anaesthesiology, Pain Medicine and Critical Care, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-0832-7433
Puneet KhannaDepartment of Anaesthesiology, Pain Medicine and Critical Care, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-9243-9963
Sulagna BhattacharjeeCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0001-8671-6875
Nishant PatelCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0001-9376-4963
Ajisha AravindanCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0003-1071-8596
Anju GuptaCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0003-1726-1488
Yudhyavir SinghCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-5101-7609
Venkata GaneshCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0001-8265-5198
Rakesh KumarCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-1539-8264
Arshed AyubCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-8441-2509
Shailender KumarCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0003-1140-5444
Kellika PrakashCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-2022-3100
Vineeta VenkateswaranCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0003-2234-8035
Debesh BhoiCritical and Intensive Care, JPN Apex Trauma Centre, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0003-2047-3115
Manish SonejaDepartment of Medicine, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-8619-7929
Purva MathurDepartment of Laboratory Medicine, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0003-4429-3688
Rajesh MalhotraDepartment of Orthopaedics, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0001-5971-003X
Naveet WigDepartment of Medicine, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-6603-601X
Randeep GuleriaDepartment of Pulmonary and Sleep Medicine, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-4213-0052
Anjan TrikhaDepartment of Anaesthesiology, Pain Medicine and Critical Care, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-6001-8486

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveA large number of studies describing the clinicoepidemiological features of coronavirus disease-2019 (COVID-19) patients are available but very few studies have documented similar features of the deceased. This study was aimed to describe the clinicoepidemiological features and the causes of mortality of COVID-19 deceased patients admitted in a dedicated COVID center in India. METHODOLOGY: This was a retrospective study done in adult deceased patients admitted in COVID ICU from April 4 to July 24, 2020. The clinical features, comorbidities, complications, and causes of mortality in these patients were analyzed. Pediatric deceased were analyzed separately.

resultsA total of 654 adult patients were admitted in the ICU during the study period and ICU mortality was 37.7% (247/654). Among the adult deceased, 65.9% were males with a median age of 56 years [interquartile range (IQR), 41.5-65] and 94.74% had one or more comorbidities, most common being hypertension (43.3%), diabetes mellitus (34.8%), and chronic kidney disease (20.6%). The most common presenting features in these deceased were fever (75.7%), cough (68.8%), and shortness of breath (67.6%). The mean initial sequential organ failure assessment score was 9.3 ± 4.7 and 24.2% were already intubated at the time of admission. The median duration of hospital stay was 6 days (IQR, 3-11). The most common cause of death was sepsis with multi-organ failure (55.1%) followed by severe acute respiratory distress syndrome (ARDS) (25.5%). All pediatric deceased had comorbid conditions and the most common cause of death in this group was severe ARDS.

conclusionIn this cohort of adult deceased, most were young males with age less than 65 years with one or more comorbidities, hypertension being the most common. Only 5% of the deceased had no comorbidities. Sepsis with multi-organ dysfunction syndrome was the most common cause of death. HOW TO CITE THIS ARTICLE: Aggarwal R, Bhatia R, Kulshrestha K, Soni KD, Viswanath R, Singh AK,

Indexed as

Clinicoepidemiological featuresComorbiditiesCOVID-19 deceasedICUMortality analysisMulti-organ dysfunction syndrome

Identifiers

PMID34316140
PMCPMC8286396

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.