ArticleThe ISME journal2022
Ammonia-oxidizing archaea possess a wide range of cellular ammonia affinities.
Article in The ISME journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 218 citations in OpenAlex.
- Oxygen production as an electron overflow pathway in ammonia-oxidizing archaea.Science advances · 2026Article
- Linking Abundance and Activity of Ammonia-Oxidising Bacteria and Archaea in an Agriculturally Impacted First-Order Stream.Environmental microbiology · 2026Article
- Ammonia monooxygenase: a work in progress.Chemical science · 2026Review
- Structurally diverse biological nitrification inhibitors display distinct modes of inhibition in ammonia-oxidizing bacteria.FEMS microbiology ecology · 2026Article
- A novel North Sea ammonia-oxidizing archaeon Nitrosarchaeum marinum leverages a high abundance of transport systems to grow over a wide salinity range.FEMS microbiology ecology · 2026Article
- Ammonia oxidizers offset acidification stress via adaptive substrate affinity in aquatic ecosystems.Nature communications · 2026Article
- Kinetic plasticity of nitrite-oxidizing bacteria containing cytoplasmic nitrite oxidoreductase.The ISME journal · 2026Article
- Hypoosmolarity inhibits ammonia oxidation by terrestrial and freshwater Nitrosopumilaceae members.The ISME journal · 2026Article
- Disturbance reshapes functional redundancy and accelerates nitrification in soil nitrifying communities.The ISME journal · 2026Article
- Copper availability controls niche differentiation between comammoxISME communications · 2026Article
- Environmental distribution, physiology and genomic adaptations of arctic ammonia-oxidizing archaea.Frontiers in microbiology · 2026Article
- The hidden potential of archaea in carbon and nitrogen cycling in agricultural soils: a review.Frontiers in microbiology · 2026Review
- Dynamics and Eco-Genomics of Baltic Sea Nitrifiers: Seasonality, Niches, Interactions and Genomic Uniqueness.Environmental microbiology · 2026Article
- Unique characteristics of acid-tolerant comammox bacteria revealed by multi-omics analyses.ISME communications · 2026Article
- Oxygen production via nitric oxide dismutation in diverse ammonia oxidizers.ISME communications · 2026Article
- Structural insights into the catalytic mechanism of ammonia monooxygenase.Nature communications · 2025Article
- Floodplain nitrifiers harbor the genetic potential for utilizing a wide range of organic nitrogen compounds.mSystems · 2025Article
- The Human Archaeome: Commensals, Opportunists, or Emerging Pathogens?Pathogens (Basel, Switzerland) · 2025Review
- Diversity and characterization of the ammonia-oxidizing bacteria responsible for nitrification in tea field soils.Scientific reports · 2025Article
- Microplastic impacts archaeal abundance, microbial communities, and their network connectivity in a Sub-Saharan soil environment.FEMS microbiology ecology · 2025Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 5 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrification, the oxidation of ammonia to nitrate, is an essential process in the biogeochemical nitrogen cycle. The first step of nitrification, ammonia oxidation, is performed by three, often co-occurring guilds of chemolithoautotrophs: ammonia-oxidizing bacteria (AOB), archaea (AOA), and complete ammonia oxidizers (comammox). Substrate kinetics are considered to be a major niche-differentiating factor between these guilds, but few AOA strains have been kinetically characterized. Here, the ammonia oxidation kinetic properties of 12 AOA representing all major cultivated phylogenetic lineages were determined using microrespirometry. Members of the genus Nitrosocosmicus have the lowest affinity for both ammonia and total ammonium of any characterized AOA, and these values are similar to previously determined ammonia and total ammonium affinities of AOB. This contrasts previous assumptions that all AOA possess much higher substrate affinities than their comammox or AOB counterparts. The substrate affinity of ammonia oxidizers correlated with their cell surface area to volume ratios. In addition, kinetic measurements across a range of pH values supports the hypothesis that-like for AOB-ammonia and not ammonium is the substrate for the ammonia monooxygenase enzyme of AOA and comammox. Together, these data will facilitate predictions and interpretation of ammonia oxidizer community structures and provide a robust basis for establishing testable hypotheses on competition between AOB, AOA, and comammox.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.