Evidence map›Paper›PMID 34315852›Full record

ArticleCell death & disease2021

Super-resolution microscopy reveals that Na

Kristoffer Bernhem, Jacopo M Fontana, Daniel Svensson, Liang Zhang, Linnéa M Nilsson, Lena Scott, Hans Blom, Hjalmar Brismar, Anita Aperia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. NaInternational journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kristoffer Bernhem *Science for Life Laboratory, Department of Applied Physics, Royal Institute of Technology, Solna, Sweden.
Jacopo M Fontana *Science for Life Laboratory, Department of Applied Physics, Royal Institute of Technology, Solna, Sweden.
Daniel Svensson *Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.ORCID 0000-0001-6670-2142
Liang Zhang *Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.
Linnéa M NilssonScience for Life Laboratory, Department of Applied Physics, Royal Institute of Technology, Solna, Sweden.
Lena ScottScience for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.
Hans BlomScience for Life Laboratory, Department of Applied Physics, Royal Institute of Technology, Solna, Sweden.ORCID 0000-0002-5584-9170
Hjalmar BrismarScience for Life Laboratory, Department of Applied Physics, Royal Institute of Technology, Solna, Sweden. brismar@kth.se.ORCID 0000-0003-0578-4003
Anita AperiaScience for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.
Science for Life Laboratory · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of the apoptotic pathway is a major cause of progressive loss of function in chronic diseases such as neurodegenerative and diabetic kidney diseases. There is an unmet need for an anti-apoptotic drug that acts in the early stage of the apoptotic process. The multifunctional protein Na

Indexed as

ApoptosisCytoprotectionMicroscopySignal TransductionAnimalsbcl-2-Associated X Proteinbcl-Associated Death Proteinbcl-X ProteinCalcium-Calmodulin-Dependent Protein KinasesCytosolEpithelial CellsGlucoseKidneyMaleMitochondriaModels, Biologicalbcl-2-Associated X Proteinbcl-Associated Death Proteinbcl-X ProteinCalcium-Calmodulin-Dependent Protein KinasesGlucoseOuabainProto-Oncogene Proteins c-aktSodium-Potassium-Exchanging ATPase

Identifiers

PMID34315852
PMCPMC8316575
OpenAlexW3185553578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.