Evidence map›Paper›PMID 34315715›Full record

ArticleBJGP open2021

Clinical judgment of GPs for the diagnosis of dementia: a diagnostic test accuracy study.

Samuel Thomas Creavin, Judy Haworth, Mark Fish, Sarah Cullum, Anthony Bayer, Sarah Purdy, Yoav Ben-Shlomo

Open access · goldAbstract read
In one paragraph

Article in BJGP open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
10.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Samuel Thomas CreavinPopulation Health Sciences, University of Bristol, Bristol, UK sam.creavin@bristol.ac.uk.
Judy HaworthPopulation Health Sciences, University of Bristol, Bristol, UK.
Mark FishRoyal Devon and Exeter NHS Foundation Trust, Exeter, UK.
Sarah CullumDepatment of Psychological Medicine, School of Medicine, The University of Auckland, Grafton, New Zealand.
Anthony BayerSchool of Medicine, Cardiff University, Cardiff, UK.
Sarah PurdyPopulation Health Sciences, University of Bristol, Bristol, UK.
Yoav Ben-ShlomoPopulation Health Sciences, University of Bristol, Bristol, UK.
Institute of Population and Public Health · CAIndiana University School of MedicineRoyal Devon & Exeter NHS Foundation Trust · GBUniversity of Auckland · NZUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGPs often report using clinical judgment to diagnose dementia.

aimTo investigate the accuracy of GPs' clinical judgment for the diagnosis of dementia. DESIGN &

settingDiagnostic test accuracy study, recruiting from 21 practices around Bristol, UK.

methodThe clinical judgment of the treating GP (index test) was based on the information immediately available at their initial consultation with a person aged ≥70 years who had cognitive symptoms. The reference standard was an assessment by a specialist clinician, based on a standardised clinical examination and made according to the 10th revision of the International Classification of Diseases (ICD-10) criteria for dementia.

resultsA total of 240 people were recruited, with a median age of 80 years (interquartile range [IQR] 75-84 years), of whom 126 (53%) were men and 132 (55%) had dementia. The median duration of symptoms was 24 months (IQR 12-36 months) and the median Addenbrooke's Cognitive Examination III (ACE-III) score was 75 (IQR 65-87). GP clinical judgment had sensitivity 56% (95% confidence interval [CI] = 47% to 65%) and specificity 89% (95% CI = 81% to 94%). Positive likelihood ratio was higher in people aged 70-79 years (6.5, 95% CI = 2.9 to 15) compared with people aged ≥80 years (3.6, 95% CI = 1.7 to 7.6), and in women (10.4, 95% CI = 3.4 to 31.7) compared with men (3.2, 95% CI = 1.7 to 6.2), whereas the negative likelihood ratio was similar in all groups.

conclusionA GP clinical judgment of dementia is specific, but confirmatory testing is needed to exclude dementia in symptomatic people whom GPs judge as not having dementia.

Indexed as

dementiageneral practicemedical history takingsensitivity and specificitysymptom assessment

Identifiers

PMID34315715
PMCPMC8596317
OpenAlexW3183900947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.