Evidence map›Paper›PMID 34315415›Full record

Trial reportBMC infectious diseases2021

A multicentre interventional study to assess blood-borne viral infections in Belgian prisons.

Dana Busschots, Cécile Kremer, Rob Bielen, Özgür M Koc, Leen Heyens, Christian Brixko, Pierre Laukens, Hans Orlent, Pascal Bilaey, Francis De Smet and 6 more

Registry-linked trialOpen access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04366492 (Prevalence of Blood Borne Viral Infections), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04366492 nacompletednot on this map

Prevalence of Blood Borne Viral Infections (HBV/HCV/HIV) in the Belgian Prison System

TypeinterventionalSponsorHasselt UniversityRan2019 to 2020Enrolled3,045ConditionsHepatitis C, Hepatitis B, HIV InfectionsArmsPrevalence of blood borne viral infections (HBV/HCV/HIV)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Dana BusschotsFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium. dana.busschots@uhasselt.be.ORCID https://orcid.org/0000-0003-0887-4119
Cécile KremerInteruniversity Institute for Biostatistics and statistical Bioinformatics (I-Biostat), Data Science Institute, Hasselt University, Diepenbeek, Belgium.
Rob BielenFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.
Özgür M KocFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.
Leen HeyensFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.
Christian BrixkoDepartment of Gastroenterology and Hepatology, CHR Citadelle, Liège, Belgium.
Pierre LaukensDienst Coördinatie Medische Zorg, Federale Overheidsdienst Justitie, Brussel, Belgium.
Hans OrlentDienst Coördinatie Medische Zorg, Federale Overheidsdienst Justitie, Brussel, Belgium.
Pascal BilaeyDienst Coördinatie Medische Zorg, Federale Overheidsdienst Justitie, Brussel, Belgium.
Francis De SmetDienst Coördinatie Medische Zorg, Federale Overheidsdienst Justitie, Brussel, Belgium.
Geert HellemansDienst Coördinatie Medische Zorg, Federale Overheidsdienst Justitie, Brussel, Belgium.
Gaetan MuyldermansEpidemiology and Public Health, Sciensano, Brussels, Belgium.
Luk Van BaelenEpidemiology and Public Health, Sciensano, Brussels, Belgium.
Niel HensInteruniversity Institute for Biostatistics and statistical Bioinformatics (I-Biostat), Data Science Institute, Hasselt University, Diepenbeek, Belgium.
Hans Van VlierbergheDepartment of Gastroenterology and Hepatology, UZ Gent, Ghent, Belgium.
Geert RobaeysFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.
Service Public Fédéral Technologie de l'Information et de la Communication · BEZiekenhuis Oost-Limburg · BEGhent University Hospital · BEMaastricht University Medical Centre · NLSciensano (Belgium) · BEHasselt University · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevalence data on viral hepatitis B (HBV), hepatitis C (HCV), and HIV infection in prison are often scarce or outdated. There is currently no systematic screening for these blood-borne viral infections (BBV) in Belgian prisons. There is an urgency to assess the prevalence of these BBV to inform policymakers and public healthcare.

methodsThis was a multicentre, interventional study to assess the prevalence of BBV using opt-in screening in prisons across Belgium, April 2019 - March 2020. Prisoners were tested using a finger prick and BBV risk factors were assessed using a questionnaire. A generalized linear mixed model was used to investigate the association between the various risk factors and HCV.

resultsIn total, 886 prisoners from 11 Belgian prisons were screened. Study uptake ranged from 16.9 to 35.4% in long-term facilities. The prevalence of HCV antibodies (Ab), hepatitis B surface antigen (Ag) and HIV Ab/Ag was 5.0% (44/886), 0.8% (7/886), and 0.2% (2/886). The adjusted odds for HCV Ab were highest in prisoners who ever injected (p < 0.001; AOR 24.6 CI 95% (5.5-215.2). The prevalence of detectable HCV RNA in the total cohort was 2.1% (19/886). Thirteen (68.4%) prisoners were redirected for follow-up of their HCV infection.

conclusionsOpt-in testing for viral hepatitis B, C and HIV was relatively well-accepted in prisons. Compared with the general population, prisoners have a higher prevalence of infection with BBV, especially for HCV. Systematic screening for these BBV should be recommended in all prisons, preferably using opt-out to optimize screening uptake.

trial registrationRetrospectively registered at clinical trials NCT04366492 April 29, 2020.

Indexed as

Hepatitis BHepatitis CHIV-1HIV InfectionsPrisonersBelgiumHepatitis C AntibodiesHumansPrevalencePrisonsRisk FactorsHepatitis C AntibodiesBlood borne viral infectionsHepatitis BHepatitis CHIVPrisonRecommendationsScreening

Identifiers

PMID34315415
PMCPMC8314587
OpenAlexW3184597560

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.