Evidence map›Paper›PMID 34315280›Full record

ArticleBone & joint open2021

CT-based volumetric assessment of rotator cuff muscle in shoulder arthroplasty preoperative planning.

Jean-David Werthel, François Boux de Casson, Valérie Burdin, George S Athwal, Luc Favard, Jean Chaoui, Gilles Walch

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Bone & joint open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07520721 (A Randomised, Multicentre, Prospective, Non-inferiority Clinical Study Analysing Outcomes of a Cemented Pegged Polyethylene Glenoid Component Versus a Hybrid Polyethylene and Trabecular Titanium Glenoid Component in Patients With Osteoarthritis Treated With an Anatomical SMR Stemless Shoulder Arthroplasty), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07520721 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Randomised, Multicentre, Prospective, Non-inferiority Clinical Study Analysing Outcomes of a Cemented Pegged Polyethylene Glenoid Component Versus a Hybrid Polyethylene and Trabecular Titanium Glenoid Component in Patients With Osteoarthritis Treated With an Anatomical SMR Stemless Shoulder Arthroplasty

TypeinterventionalSponsorSpaarne GasthuisRan2025 to 2036Enrolled94ConditionsGlenohumeral OsteoarthritisArmsAnatomic total shoulder arthroplasty with cemented all-polyethylene pegged glenoid, Anatomic total shoulder arthroplasty with hybrid trabecular titanium central-peg glenoid
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 3 countries.

Jean-David WerthelHôpital Ambroise Paré, Boulogne-Billancourt, France.ORCID https://orcid.org/0000-0002-1123-1758
François Boux de CassonWright Medical, Montbonnot, France.ORCID https://orcid.org/0000-0001-7567-2651
Valérie BurdinLaboratory of Medical Information Processing, Brest, France.
George S AthwalRoth McFarlane Hand and Upper Limb Center, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Luc FavardCHRU de Tours, Tours, France.
Jean ChaouiWright Medical, Montbonnot, France.
Gilles WalchCentre Orthopédique Santy, Lyon, France.
Centre Hospitalier Universitaire de Tours · FRHôpital Ambroise-Paré · FRHôpital Privé Jean Mermo · FRLaboratoire de Traitement de l'Information Médicale · FRNational Society of Professional Engineers · USStryker (United States) · USWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aim of this study was to describe a quantitative 3D CT method to measure rotator cuff muscle volume, atrophy, and balance in healthy controls and in three pathological shoulder cohorts.

methodsIn all, 102 CT scans were included in the analysis: 46 healthy, 21 cuff tear arthropathy (CTA), 18 irreparable rotator cuff tear (IRCT), and 17 primary osteoarthritis (OA). The four rotator cuff muscles were manually segmented and their volume, including intramuscular fat, was calculated. The normalized volume (NV) of each muscle was calculated by dividing muscle volume to the patient's scapular bone volume. Muscle volume and percentage of muscle atrophy were compared between muscles and between cohorts.

resultsRotator cuff muscle volume was significantly decreased in patients with OA, CTA, and IRCT compared to healthy patients (p < 0.0001). Atrophy was comparable for all muscles between CTA, IRCT, and OA patients, except for the supraspinatus, which was significantly more atrophied in CTA and IRCT (p = 0.002). In healthy shoulders, the anterior cuff represented 45% of the entire cuff, while the posterior cuff represented 40%. A similar partition between anterior and posterior cuff was also found in both CTA and IRCT patients. However, in OA patients, the relative volume of the anterior (42%) and posterior cuff (45%) were similar.

conclusionThis study shows that rotator cuff muscle volume is significantly decreased in patients with OA, CTA, or IRCT compared to healthy patients, but that only minimal differences can be observed between the different pathological groups. This suggests that the influence of rotator cuff muscle volume and atrophy (including intramuscular fat) as an independent factor of outcome may be overestimated. Cite this article:

Indexed as

3D CT scanatrophyfatty infiltrationmuscle volumeoccupation ratiorotator cuff muscleshoulder arthroplastytangent signvolumetric analysis

Identifiers

PMID34315280
PMCPMC8329519
OpenAlexW3186467174

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.