Evidence map›Paper›PMID 34315274›Full record

ReviewOpen biology2021

Ghrelin octanoylation by ghrelin

Tasha R Davis, Mariah R Pierce, Sadie X Novak, James L Hougland

Open access · goldAbstract readReview
In one paragraph

Review in Open biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. [Clinical analysis of nutritional components in children with acute leukemia].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Role of the Ghrelin System in Colorectal Cancer.International journal of molecular sciences · 2022
    Review
  16. "Sibling" battle or harmony: crosstalk between nesfatin-1 and ghrelin.Cellular and molecular life sciences : CMLS · 2022
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tasha R DavisDepartment of Chemistry, Syracuse University, Syracuse, NY 13244 USA.
Mariah R PierceDepartment of Chemistry, Syracuse University, Syracuse, NY 13244 USA.
Sadie X NovakDepartment of Chemistry, Syracuse University, Syracuse, NY 13244 USA.
James L HouglandDepartment of Chemistry, Syracuse University, Syracuse, NY 13244 USA.
Syracuse University · US

Funding

Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-AcyltransferaseR01GM134102 · NIGMS · SYRACUSE UNIVERSITY · PI CHISHOLM, JOHN DANIEL, HOUGLAND, JAMES · 2019 to 2021
$1.0M
NIGMS NIH HHS R01 GM134102
6 · The paper itself

Abstract

The acylated peptide hormone ghrelin impacts a wide range of physiological processes but is most well known for controlling hunger and metabolic regulation. Ghrelin requires a unique posttranslational modification, serine octanoylation, to bind and activate signalling through its cognate GHS-R1a receptor. Ghrelin acylation is catalysed by ghrelin

Indexed as

Protein Processing, Post-TranslationalSignal TransductionAcylationAcyltransferasesAnimalsBinding SitesCarrier ProteinsDrug DevelopmentGhrelinHumansModels, MolecularNeurosecretory SystemsProtein BindingProtein Interaction Domains and MotifsStructure-Activity RelationshipSubstrate SpecificityAcyltransferasesCarrier ProteinsGhrelinMBOAT4 protein, humanghrelinghrelin O-acyltransferaseGHS-R1amembrane-bound O-acyltransferaseneuroendocrinologyprotein acylation

Identifiers

PMID34315274
PMCPMC8316800
OpenAlexW3185766400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.