Evidence map›Paper›PMID 34315014›Full record

ArticleDrug and alcohol dependence2021

Predictors of having naloxone in urban and rural Oregon findings from NHBS and the OR-HOPE study.

Lauren Lipira, Gillian Leichtling, Ryan R Cook, Judith M Leahy, E Roberto Orellana, P Todd Korthuis, Timothy W Menza

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Correlates of Rural Naloxone Possession Among People Who Use Drugs: A Multi-State Cross-Sectional Analysis.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026
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  11. An exploratory study of a hands-on naloxone training for rural clinicians and staff.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Lauren LipiraRegional Research Institute, Portland State University, 1600 SW 4(th)Avenue, Suite 900, Portland, OR, 97201, USA; Public Health Division, Oregon Health Authority, 800 NE Oregon Street, Portland, OR, 97232, USA. Electronic address: Lauren.E.Lipira@dhsoha.state.or.us.
Gillian LeichtlingComagine Health, 650 NE Holladay, Suite 1700, Portland, OR, 97232, USA. Electronic address: GLeichtling@comagine.org.
Ryan R CookDepartment of Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA. Electronic address: cookry@ohsu.edu.
Judith M LeahyPublic Health Division, Oregon Health Authority, 800 NE Oregon Street, Portland, OR, 97232, USA. Electronic address: Judith.M.LEAHY@dhsoha.state.or.us.
E Roberto OrellanaRegional Research Institute, Portland State University, 1600 SW 4(th)Avenue, Suite 900, Portland, OR, 97201, USA. Electronic address: orellana@pdx.edu.
P Todd KorthuisDepartment of Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA. Electronic address: korthuis@ohsu.edu.
Timothy W MenzaPublic Health Division, Oregon Health Authority, 800 NE Oregon Street, Portland, OR, 97232, USA; Department of Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA. Electronic address: TIMOTHY.W.MENZA@dhsoha.state.or.us.
Oregon Health Authority · USOregon Health & Science University · USEagle Mount · USPortland State University · US

Funding

Western States Node of the National Drug Abuse Treatment Clinical Trials NetworkU10DA015815 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCCARTY, DENNIS, SORENSEN, JAMES L · 2002 to 2015
$25.2M
Western States Node of the National Drug Abuse Treatment Clinical Trials Network (TMS for CUD) UG1DA015815 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Keith N. Humphreys, Philip Todd Korthuis · 2015 to 2026
$24.6M
Peer-based Retention of people who Use Drugs in Rural Research (PROUD-R2)U01TR002631 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI KORTHUIS, PHILIP TODD, YOUNG, APRIL MARIE · 2018 to 2023
$5.2M
NW Center of Excellence & K12 in Patient Centered Learning Health Systems ScienceK12HS026370 · AHRQ · OREGON HEALTH & SCIENCE UNIVERSITY · PI EDEN, KAREN BEEKMAN, GUISE, JEANNE-MARIE · 2018 to 2022
$4.0M
Oregon HIV/Hepatitis and Opioid Prevention and Engagement (OR-HOPE) Study Cost ExtensionUH3DA044831 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KORTHUIS, PHILIP TODD · 2019 to 2022
$4.0M
Oregon HIV/Hepatitis and Opioid Prevention and Engagement (OR-HOPE) StudyUG3DA044831 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KORTHUIS, PHILIP TODD · 2017 to 2018
$895k
National HIV Behavioral Surveillance ProjectU62PS005087 · PS · PUBLIC HEALTH SERVICES · PI SCHAFER, SEAN · 2016 to 2016
$103k
AHRQ HHS K12 HS026370NCATS NIH HHS U01 TR002631NCHHSTP CDC HHS U62 PS005087NIDA NIH HHS U10 DA015815NIDA NIH HHS UG1 DA015815NIDA NIH HHS UG3 DA044831NIDA NIH HHS UH3 DA044831
6 · The paper itself

Abstract

purposeNaloxone is an opioid antagonist that can be effectively administered by bystanders to prevent overdose. We determined the proportion of people who had naloxone and identified predictors of naloxone ownership among two samples of people who inject drugs (PWID) who use opioids in Portland and rural Western Oregon. BASIC PROCEDURES: We used data from participants in Portland's National HIV Behavioral Surveillance (NHBS, N = 477) and the Oregon HIV/Hepatitis and Opioid Prevention and Engagement Study (OR-HOPE, N = 133). For each sample, we determined the proportion of participants who had naloxone and estimated unadjusted and adjusted relative risk of having naloxone associated with participant characteristics. MAIN

findingsSixty one percent of NHBS and 30 % of OR-HOPE participants had naloxone. In adjusted analysis, having naloxone was associated with female gender, injecting goofballs (compared to heroin alone), housing stability, and overdose training in the urban NHBS sample, and having naloxone was associated with drug of choice, frequency of injection, and race in the rural OR-HOPE sample. In both samples, having naloxone was crudely associated with SSP use, but this was attenuated after adjustment. PRINCIPAL

conclusionsNaloxone ownership was insufficient and highly variable among two samples of PWID who use opioids in Oregon. People who use methamphetamine, males, and people experiencing homelessness may be at increased risk for not having naloxone and SSP may play a key role in improving access.

Indexed as

Drug OverdoseOpioid-Related DisordersSubstance Abuse, IntravenousFemaleHumansMaleNaloxoneNarcotic AntagonistsOregonNaloxoneNarcotic AntagonistsIDUNaloxoneOpioidsOverdoseRegional

Identifiers

PMID34315014
PMCPMC8464511
OpenAlexW3183398271

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.