Evidence map›Paper›PMID 34314855›Full record

ArticleContemporary clinical trials2021

The mobile assistance for regulating smoking (MARS) micro-randomized trial design protocol.

Inbal Nahum-Shani, Lindsey N Potter, Cho Y Lam, Jamie Yap, Alexander Moreno, Rebecca Stoffel, Zhenke Wu, Neng Wan, Walter Dempsey, Santosh Kumar and 4 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Momentary mindfulness versus distraction coping messages to reduce cannabis craving among young adults: A microrandomized trial.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  7. Article
  8. Towards the Science of Engagement with Digital Interventions.Current directions in psychological science · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Engagement in digital interventions.The American psychologist · 2022
    Article
  15. Article
  16. Article
  17. Hybrid Experimental Designs for Intervention Development: What, Why, and How.Advances in methods and practices in psychological science
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Inbal Nahum-ShaniInstitute for Social Research, University of Michigan, Ann Arbor, MI, United States of America. Electronic address: inbal@umich.edu.
Lindsey N PotterHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, United States of America.
Cho Y LamHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, United States of America.
Jamie YapInstitute for Social Research, University of Michigan, Ann Arbor, MI, United States of America.
Alexander MorenoCollege of Computing, Georgia Institute of Technology, Atlanta, GA, United States of America.
Rebecca StoffelHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, United States of America.
Zhenke WuSchool of Public Health, University of Michigan, Ann Arbor, MI, United States of America.
Neng WanDepartment of Geography, University of Utah, Salt Lake City, UT, United States of America.
Walter DempseySchool of Public Health, University of Michigan, Ann Arbor, MI, United States of America.
Santosh KumarDepartment of Computer Science, University of Memphis, Memphis, TN, United States of America.
Emre ErtinDepartment of Electrical and Computer Engineering, The Ohio State University, Columbus, OH, United States of America.
Susan A MurphyDepartments of Statistics & Computer Science, Harvard University, Cambridge, MA, United States of America.
James M RehgCollege of Computing, Georgia Institute of Technology, Atlanta, GA, United States of America.
David W WetterHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, United States of America.

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jared P Rutter · 1986 to 2026
$72.6M
Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Pilot and Mentoring CoreP50DA054039 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LINDA M COLLINS, SUSAN A MURPHY · 2021 to 2026
$18.2M
Pilot, Mentoring, and Professional Development CoreP50DA039838 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI COLLINS, LINDA M · 2015 to 2019
$13.9M
TRAINING U54EB020404 · NIBIB · UNIVERSITY OF MEMPHIS · PI KUMAR, SANTOSH · 2014 to 2018
$11.3M
TR&D3 - Rapid Translation of AI-powered Temporally Precise mHealth Interventions via Efficient and Embeddable Trustworthy Biomarker ImplementationsP41EB028242 · NIBIB · UNIVERSITY OF MEMPHIS · PI Santosh Kumar · 2020 to 2026
$9.5M
Novel Methods for Intensive Longitudinal Data in SMART Studies of Drug Abuse and HIVR01DA039901 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALMIRALL, DANIEL, NAHUM-SHANI, INBAL BILLIE · 2015 to 2024
$5.4M
Novel use of mHealth data to identify states of vulnerability and receptivity to JITAIs SupplementU01CA229437 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NAHUM-SHANI, INBAL BILLIE, WETTER, DAVID W · 2018 to 2022
$2.8M
Data-Based Methods for Just-In-Time Adaptive Interventions in Alcohol UseR01AA023187 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURPHY, SUSAN A · 2015 to 2019
$2.6M
NRSA Training CoreTL1TR002540 · NCATS · UNIVERSITY OF UTAH · PI FAGERLIN, ANGELA, FAIRFAX, KEKE CELESTE · 2018 to 2022
$1.6M
NCATS NIH HHS TL1 TR002540NCATS NIH HHS UL1 TR002538NCI NIH HHS P30 CA042014NCI NIH HHS U01 CA229437NIAAA NIH HHS R01 AA023187NIBIB NIH HHS P41 EB028242NIBIB NIH HHS U54 EB020404NIDA NIH HHS P50 DA039838NIDA NIH HHS P50 DA054039NIDA NIH HHS R01 DA039901
6 · The paper itself

Abstract

Smoking is the leading preventable cause of death and disability in the U.S. Empirical evidence suggests that engaging in evidence-based self-regulatory strategies (e.g., behavioral substitution, mindful attention) can improve smokers' ability to resist craving and build self-regulatory skills. However, poor engagement represents a major barrier to maximizing the impact of self-regulatory strategies. This paper describes the protocol for Mobile Assistance for Regulating Smoking (MARS) - a research study designed to inform the development of a mobile health (mHealth) intervention for promoting real-time, real-world engagement in evidence-based self-regulatory strategies. The study will employ a 10-day Micro-Randomized Trial (MRT) enrolling 112 smokers attempting to quit. Utilizing a mobile smoking cessation app, the MRT will randomize each individual multiple times per day to either: (a) no intervention prompt; (b) a prompt recommending brief (low effort) cognitive and/or behavioral self-regulatory strategies; or (c) a prompt recommending more effortful cognitive or mindfulness-based strategies. Prompts will be delivered via push notifications from the MARS mobile app. The goal is to investigate whether, what type of, and under what conditions prompting the individual to engage in self-regulatory strategies increases engagement. The results will build the empirical foundation necessary to develop a mHealth intervention that effectively utilizes intensive longitudinal self-report and sensor-based assessments of emotions, context and other factors to engage an individual in the type of self-regulatory activity that would be most beneficial given their real-time, real-world circumstances. This type of mHealth intervention holds enormous potential to expand the reach and impact of smoking cessation treatments.

Indexed as

Mobile ApplicationsSmoking CessationHumansMotivationRandomized Controlled Trials as TopicSmokersSmokingEngagementMicro-randomized trial (MRT)Mobile health (mHealth)Self-regulatory strategiesSmoking cessation

Identifiers

PMID34314855
PMCPMC8824313

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.