Evidence map›Paper›PMID 34314738›Full record

ReviewPharmacology, biochemistry, and behavior2021

Impact of specific serotonin receptor modulation on behavioral flexibility.

Bryan D Alvarez, Cheyenne A Morales, Dionisio A Amodeo

Open access · hybridAbstract readReview
In one paragraph

Review in Pharmacology, biochemistry, and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Response Flexibility: The Role of the Lateral Habenula.Frontiers in behavioral neuroscience · 2022
    Pooled it
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Acute psilocybin enhances cognitive flexibility in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  15. Maternal organophosphate flame retardant exposure alters the developing mesencephalic dopamine system in fetal rat.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  16. Acute psilocybin enhances cognitive flexibility in rats.bioRxiv : the preprint server for biology · 2023
    Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bryan D AlvarezCalifornia State University San Bernardino, Department of Psychology, 5500 University Parkway, San Bernardino, CA 92407, United States of America.
Cheyenne A MoralesCalifornia State University San Bernardino, Department of Psychology, 5500 University Parkway, San Bernardino, CA 92407, United States of America.
Dionisio A AmodeoCalifornia State University San Bernardino, Department of Psychology, 5500 University Parkway, San Bernardino, CA 92407, United States of America. Electronic address: dionisio.amodeo@csusb.edu.
California State University, San Bernardino · US

Funding

U-RISE at CSUSBT34GM136467 · NIGMS · CALIFORNIA STATE UNIV SAN BERNARDINO · PI Leslie Renee Amodeo, Jacob D Jones · 2020 to 2026
$2.6M
NIGMS NIH HHS T34 GM136467
6 · The paper itself

Abstract

Serotonin (5-HT) is known to play a critical role in regulation of essential neural processes, whereas more recent research highlights serotonin's modulatory effects on cognition and executive functioning. Current examinations have identified specific serotonin receptors for their direct impact on behavioral flexibility. Providing definitive evidence for the impact of specific receptor targets on behavioral flexibility is difficult, due to the range of behavioral tests used. Due to limited studies and the sheer amount of different serotonin receptor targets, beginning to bring these studies together is important for the field. Our current review of the literature aims to differentiate how modulation of specific 5-HT receptors affects behavioral flexibility. Although more studies have examined 5-HT

Indexed as

CognitionExecutive FunctionAnimalsBehavior, AnimalFemaleHumansMaleMiceRatsReceptor, Serotonin, 5-HT2AReceptor, Serotonin, 5-HT2CReceptors, SerotoninReversal LearningSerotoninReceptor, Serotonin, 5-HT2AReceptor, Serotonin, 5-HT2CReceptors, SerotoninSerotoninBehavioral flexibilityReversal learningSerotonin receptor

Identifiers

PMID34314738
PMCPMC8429145
OpenAlexW3186637878

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.