ArticlePLoS neglected tropical diseases2021
Prevalence of urogenital and intestinal schistosomiasis among school children in South-west Nigeria.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Prevalence of Schistosoma haematobium and Schistosoma mansoni co-infection in sub-saharan Africa: a systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Article
- Prevalence and associated factors of schistosomiasis among children and adolescents visiting Chitokoloki Mission Hospital of Zambezi District.BMC infectious diseases · 2025Article
- Prevalence, associated risk factors and molecular identification of urinary schistosomiasis among primary school pupils in Jama'are Local Government Area, Bauchi State, Nigeria.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Article
- Schistosoma mansoni x S. haematobium hybrids frequently infecting sub-Saharan migrants in southeastern Europe: Egg DNA genotyping assessed by RD-PCR, sequencing and cloning.PLoS neglected tropical diseases · 2025Article
- Article
- Schistosomiasis Interventions in Africa: Assessment and Systematic Review.Journal of parasitology research · 2025Review
- Prevalence of schistosomiasis among school children at Esuekyir community in the Central Region of Ghana.BMC infectious diseases · 2024Article
- Computer-aided discovery of novel SmDHODH inhibitors for schistosomiasis therapy: Ligand-based drug design, molecular docking, molecular dynamic simulations, drug-likeness, and ADMET studies.PLoS neglected tropical diseases · 2024Article
- Assessing urogenital schistosomiasis and female genital schistosomiasis (FGS) among adolescents in Anaocha, Anambra State, Nigeria: implications for ongoing control efforts.BMC public health · 2024Article
- Identification of trans-genus biomarkers for early diagnosis of intestinal schistosomiasis and progression of gut pathology in a mouse model using metabolomics.PLoS neglected tropical diseases · 2024Article
- Human schistosomiasis in Nigeria: present status, diagnosis, chemotherapy, and herbal medicines.Parasitology research · 2023Review
- Severity of Schistosoma haematobium co-infection with malaria in school-children is potentially modulated by host CD14 gene variants.BMC research notes · 2023Article
- Review of Recent Prevalence of Urogenital Schistosomiasis in Sub-Saharan Africa and Diagnostic Challenges in the Field Setting.Life (Basel, Switzerland) · 2023Review
- Intestinal schistosomiasis among secondary school students in Northern Tanzania: prevalence, infection intensity and associated risk factors.IJID regions · 2023Article
- Malaria, Urogenital Schistosomiasis, and Anaemia in Pregnant Ghanaian Women.Journal of parasitology research · 2023Article
- Article
- Neuroimmunology of Common Parasitic Infections in Africa.Frontiers in immunology · 2022Review
- Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation.European journal of medicinal chemistry · 2021Article
- Diagnostic Accuracy of Urine Test Strip and Morbidity Indicators of Urogenital Schistosomiasis in Kwara State, Nigeria.Iranian journal of parasitologyArticle
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Authors and funding
9 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe risk of co-infection with Schistosoma haematobium and S. mansoni and the potential harmful effect on morbidity and control is enhanced by the overlapping distribution of both species in sub-Saharan Africa. Despite the reported high endemicity of both species in Nigeria, studies on the spread and effect of their mixed infection are limited. Therefore, a cross-sectional survey was conducted among school children in two communities in South-west Nigeria to investigate the prevalence of mixed human schistosome infection, intensity, and possible ectopic egg elimination.
methodsUrine and stool samples were collected from consenting school children in Ilie and Ore communities of Osun State, Nigeria. Schistosoma haematobium eggs were detected in urine using the urine filtration technique, while S. mansoni eggs were detected in stool using the Kato-Katz thick smear technique.
resultsThe study enrolled 466 primary and secondary school children (211; 45.3% males vs. 255; 54.7% females; mean age 11.6 ± 3.16 years). The overall prevalence of schistosomiasis was 40% (185/466), with 19% (89/466) recording single S. haematobium infection while 9% (41/465) had a single S. mansoni infection. The geometric mean egg count for S. haematobium was 189.4 egg/10ml urine; 95% CI: range 115.9-262.9, while for S. mansoni, it was 115.7 epg; 95% CI: range 78.4-152.9. The prevalence of ectopic S mansoni (S. mansoni eggs in urine) was 4.7%, while no ectopic S. haematobium (S. haematobium eggs in stool) was recorded. Mixed infection of S. haematobium/S. mansoni had a prevalence of 9.5% (44/466). More females (54.5%) presented with S. haematobium/S. mansoni co-infection. For both parasites, males had higher infection intensity, with a significant difference observed with S. haematobium (p = 0.0004). Hematuria was significant in individuals with single S. haematobium infection (p = 0.002), mixed ectopic S. haematobium/S. mansoni (p = 0.009) and mixed S. haematobium/S. mansoni/ectopic S. mansoni (p = 0.0003).
conclusionsThese findings suggest the probability of interspecific interactions between S. haematobium and S. mansoni. Scaling up of mass administration of praziquantel and control measures in the study areas is highly desirable.
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