Evidence map›Paper›PMID 34314421›Full record

ArticlePloS one2021

Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN.

Nithya Rajagopalan, Venkateswaran N, Alex Noel Josephraj, Srithaladevi E

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Nithya RajagopalanDepartment of Biomedical Engineering, Sri Sivasubramaniya Nadar College of Engineering, Chennai, India.ORCID 0000-0002-4172-780X
Venkateswaran NDepartment of Electronics and Communication Engineering, Sri Sivasubramaniya Nadar College of Engineering, Chennai, India.
Alex Noel JosephrajDepartment of Electronic Engineering, College of Engineering, Shantou University, Shantou, China.
Srithaladevi EDepartment of Biomedical Engineering, Sri Sivasubramaniya Nadar College of Engineering, Chennai, India.
Sri Ramachandra Institute of Higher Education and Research · INShantou University · CNSri Sivasubramaniya Nadar College of Engineering

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An efficient automatic decision support system for detection of retinal disorders is important and is the need of the hour. Optical Coherence Tomography (OCT) is the current imaging modality for the early detection of retinal disorders non-invasively. In this work, a Convolution Neural Network (CNN) model is proposed to classify three types of retinal disorders namely: Choroidal neovascularization (CNV), Drusen macular degeneration (DMD) and Diabetic macular edema (DME). The hyperparameters of the model like batch size, number of epochs, dropout rate, and the type of optimizer are tuned using random search optimization method for better performance to classify different retinal disorders. The proposed architecture provides an accuracy of 97.01%, sensitivity of 93.43%, and 98.07% specificity and it outperformed other existing models, when compared. The proposed model can be used for the large-scale screening of retinal disorders effectively.

Indexed as

Neural Networks, ComputerTomography, Optical CoherenceArea Under CurveChoroidal NeovascularizationHumansMacular DegenerationMacular EdemaRetinaRetinal DiseasesROC CurveSensitivity and Specificity

Identifiers

PMID34314421
PMCPMC8315505
OpenAlexW3186706997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.