Evidence map›Paper›PMID 34314377›Full record

ArticleAging2021

Characterization of familial hypercholesterolemia in Taiwanese ischemic stroke patients.

Hsin Tung, Hsueh-Ju Lin, Po-Lin Chen, Tsai-Jung Lu, Pei-Pei Jhan, Jun-Peng Chen, Yi-Ming Chen, Chen-Chin Wu, Yung-Yang Lin, Tzu-Hung Hsiao

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hsin TungInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Hsueh-Ju LinDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Po-Lin ChenDivision of General Neurology, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan.
Tsai-Jung LuDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Pei-Pei JhanDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Jun-Peng ChenBiostatistics Task Force of Taichung Veterans General Hospital, Taichung, Taiwan.
Yi-Ming ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Chen-Chin WuDivision of Epilepsy, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan.
Yung-Yang LinInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Tzu-Hung HsiaoDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Taichung Veterans General Hospital · TWNational Yang Ming Chiao Tung University · TWFu Jen Catholic University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Familial hypercholesterolemia (FH) is a common genetic disorder characterized by a lifelong elevated low-density lipoprotein cholesterol (LDL-C) level. The relationship between FH and ischemic stroke is still controversial. We enrolled ischemic stroke patients prospectively in our neurological ward, and divided them into two groups according to LDL-C levels with a threshold of 130 mg/dl. Targeted sequencing was performed in all stroke patients for

Indexed as

AgedApolipoprotein B-100Carotid Intima-Media ThicknessCholesterol, LDLFemaleHeterozygoteHumansHyperlipoproteinemia Type IIIschemic StrokeMaleMiddle AgedMutationPhenotypeProprotein Convertase 9Receptors, LDLRisk FactorsAPOB protein, humanApolipoprotein B-100Cholesterol, LDLLDLR protein, humanPCSK9 protein, humanProprotein Convertase 9Receptors, LDLatherosclerosiscarotid intima-media thicknessfamilial hypercholesterolemiaischemic strokelow-density lipoprotein cholesterol

Identifiers

PMID34314377
PMCPMC8386562
OpenAlexW3185358735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.