Evidence map›Paper›PMID 34314261›Full record

ArticleAIDS care2022

Barriers to HIV care in Uganda and implications for universal test-and-treat: a qualitative study.

Sarah M Lofgren, Sharon Tsui, Lynn Atuyambe, Leander Ankunda, Robina Komuhendo, Nathan Wamala, Alisat Sadiq, Paul Kirumira, Diksha Srishyla, Andrew Flynn and 4 more

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Sarah M LofgrenUniversity of Minnesota, Division of Infectious Diseases and International Medicine, Department of Medicine, Minneapolis, MN, USA.
Sharon TsuiInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Lynn AtuyambeMakerere University, School of Public Health, Kampala, Uganda.
Leander AnkundaMakerere University, School of Public Health, Kampala, Uganda.
Robina KomuhendoMakerere University, School of Public Health, Kampala, Uganda.
Nathan WamalaMakerere University, School of Public Health, Kampala, Uganda.
Alisat SadiqInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Paul KirumiraInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Diksha SrishylaUniversity of Minnesota, School of Public Health, Minneapolis, MN, USA.
Andrew FlynnInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Katelyn A PastickInfectious Diseases Institute, Makerere University, Kampala, Uganda.
David B MeyaInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Noeline NakasujjaInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Carolyn PortaUniversity of Minnesota, School of Public Health, Minneapolis, MN, USA.
Makerere University · UGUniversity of Minnesota · USInfectious Diseases Institute · UG

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related MeningitisR01NS086312 · NINDS · UNIVERSITY OF MINNESOTA · PI David R Boulware, David Bisagaya Meya · 2013 to 2026
$8.3M
Infectious Disease Training in Clinical InvestigationT32AI055433 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI David R Boulware · 2003 to 2026
$6.1M
Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
Neuroinflammation and Modulating Factors in Depression and HIVK23MH121220 · NIMH · UNIVERSITY OF MINNESOTA · PI LOFGREN, SARAH · 2019 to 2022
$795k
FIC NIH HHS R25 TW009345NCATS NIH HHS UL1 TR002494NIAID NIH HHS T32 AI055433NIMH NIH HHS K23 MH121220NINDS NIH HHS R01 NS086312
6 · The paper itself

Abstract

Achieving universal HIV test-and-treat will require targeted interventions for those with worse outcomes, including advanced HIV. We conducted qualitative, semi-structured interviews with healthcare workers (HCWs) and people living with HIV (PLWH) at 5 HIV clinics in Kampala, Uganda, to understand barriers to care. PLWH enrolled started/restarted on HIV treatment ≤3 months prior. PLWH were grouped as 1) "ART-experienced" or those restarted therapy after ≥12 months off, 2) ART naïve CD4 count <100 cells/uL "late presenters" or 3) ART naïve CD4 count >350 cells/uL "early presenters". In-depth interviews were conducted in Luganda, translated, and transcribed verbatim. Between May and August 2017, 58 PLWH and 20 HCWs were interviewed. High stigma and low social support emerged as themes among all as barriers to care. Alcohol abuse was a barrier for men. Fear of domestic violence and abandonment were barriers for women, limiting disclosure of their HIV status to their male partners. Clinic factors such as rapport with staff, distance, efficiency, and privacy impacted care. Future interventions to decrease delayed ART initiation should target stigma and social support. Assisted disclosure, contact tracing, and alcohol abuse treatment should be implemented. Strengthening client support, reducing wait times, and increasing privacy assurances would improve care-seeking behaviors.

Indexed as

AlcoholismHIV InfectionsCD4 Lymphocyte CountFemaleHumansMaleQualitative ResearchSocial StigmaUgandaAfricabarriers to carehealth systemsHIVlate presentation

Identifiers

PMID34314261
PMCPMC8792098
OpenAlexW3185299986

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.