Evidence map›Paper›PMID 34314229›Full record

ReviewAntioxidants & redox signaling2021

Aging-Induced Impairment of Vascular Function: Mitochondrial Redox Contributions and Physiological/Clinical Implications.

Evan Paul Tracy, William Hughes, Jason E Beare, Gabrielle Rowe, Andreas Beyer, Amanda Jo LeBlanc

Open access · greenAbstract readReview
In one paragraph

Review in Antioxidants & redox signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  4. Mechanisms underlying end-organ injury in sleep apnoea.The European respiratory journal · 2026
    Review
  5. Article
  6. Review
  7. Review
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  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Applications of 3D printing in aging.International journal of bioprinting · 2023
    Review
  17. Article
  18. Article
  19. State of the field: cellular and exosomal therapeutic approaches in vascular regeneration.American journal of physiology. Heart and circulatory physiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Evan Paul TracyDepartment of Physiology, University of Louisville, Louisville, Kentucky, USA.ORCID 0000-0002-6689-0216
William HughesDepartment of Medicine and Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Jason E BeareCardiovascular Innovation Institute, University of Louisville, Louisville, Kentucky, USA.
Gabrielle RoweDepartment of Physiology, University of Louisville, Louisville, Kentucky, USA.
Andreas BeyerDepartment of Medicine and Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Amanda Jo LeBlancDepartment of Physiology, University of Louisville, Louisville, Kentucky, USA.
University of Louisville · USMedical College of Wisconsin · US

Funding

Pivotal Role of Mitochondrial Telomerase in Regulation of Vascular Tone and Redox HomeostasisR01HL133029 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI BEYER, ANDREAS M · 2017 to 2021
$2.2M
Critical role of Mitochondrial Fission/Fusion in Regulation of Microvascular Endothelial FunctionR01HL157025 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI BEYER, ANDREAS M · 2021 to 2024
$2.1M
Anesthesiology Research Training ProgramT32GM089586 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI EBERT, THOMAS JAY · 2010 to 2019
$1.5M
NHLBI NIH HHS R01 HL133029NHLBI NIH HHS R01 HL157025NIGMS NIH HHS T32 GM089586
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingAnimalsEndothelium, VascularHumansMitochondriaOxidation-Reductionagingendothelial dysfunctionmitochondrial dysfunctionoxidative stressreactive oxygen speciesvasodilation

Identifiers

PMID34314229
PMCPMC8905248
OpenAlexW3183635470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.