Evidence map›Paper›PMID 34313961›Full record

ArticleAging clinical and experimental research2022

The Montreal Cognitive Assessment (MoCA): updated norms and psychometric insights into adaptive testing from healthy individuals in Northern Italy.

Edoardo Nicolò Aiello, Chiara Gramegna, Antonella Esposito, Valentina Gazzaniga, Stefano Zago, Teresa Difonzo, Ottavia Maddaluno, Ildebrando Appollonio, Nadia Bolognini

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05902065 (Biomarkers of Rehabilitation Outcome in Patients With Parkinson's Disease), which is not on this map. Cited by 86 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05902065 naunknown statusnot on this map

Biomarkers of Rehabilitation Outcome in Patients With Parkinson's Disease: Effect of a Customized Protocol on Treadmill Training With and Without Augmented Virtual Reality Application, a Randomized Controlled Trial

TypeinterventionalSponsorUniversity of FlorenceRan2022 to 2023Enrolled60ConditionsParkinson Disease, Gait, Festinating, Fall Due to Loss of Equilibrium, Gait, UnsteadyArmsAVR Treadmill training with C-Mill, Conventional Treadmill training with C-Mill
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Psychometrics and diagnostics of Italian cognitive screening tests: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Pooled it
  2. Translations and cultural adaptations of the Montreal Cognitive Assessment: a systematic and qualitative review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Pooled it
  3. Trial
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  6. Brief tests for the assessment of language-executive functions: normative data for the Italian population.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  9. Validation of the Italian version of the In-Person Telephone Interview for Cognitive Status (IP-TICS).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  11. Normative data and clinical usability of the brief examination of social abilities: a novel screening test for social cognition.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  14. Updated Italian norms for the Paired-Associate Learning Test (PALT).Aging clinical and experimental research · 2026
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  16. Brain morphometry and cognition in late-onset glutaric aciduria type 1: scoping review and novel insights from a case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Edoardo Nicolò Aiello *School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy. e.aiello5@campus.unimib.it.ORCID http://orcid.org/0000-0001-8902-7733
Chiara Gramegna *Department of Psychology, and NeuroMi - Milan Center for Neuroscience, University of Milano Bicocca, Milan, Italy.
Antonella EspositoDepartment of Psychology, and NeuroMi - Milan Center for Neuroscience, University of Milano Bicocca, Milan, Italy.
Valentina GazzanigaDepartment of Psychology, and NeuroMi - Milan Center for Neuroscience, University of Milano Bicocca, Milan, Italy.
Stefano ZagoFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Teresa DifonzoFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Ottavia MaddalunoDepartment of Psychology, Sapienza University of Rome, Rome, Italy.
Ildebrando AppollonioSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Nadia BologniniDepartment of Psychology, and NeuroMi - Milan Center for Neuroscience, University of Milano Bicocca, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe availability of fine-grained, culture-specific psychometric outcomes can favor the interpretation of scores of the Montreal Cognitive Assessment (MoCA), the most frequently used instrument to screen for mild cognitive dysfunctions in both instrumental and non-instrumental domains. This study thus aimed at providing: (i) updated, region-specific norms for the Italian MoCA, by also (ii) comparing them to pre-existing ones with higher geographical coverage; (iii) information on sensitivity and discriminative capability at the item level.

methodsFive hundred and seventy nine healthy individuals from Northern Italy (208 males, 371 females; age: 63.4 ± 15, 21-96; education: 11.3 ± 4.6, 1-25) were administered the MoCA. Item Response Theory (IRT) was adopted to assess item difficulty and discrimination. Normative values were derived by means of the Equivalent Scores (ESs) method, applied to the MoCA and its sub-scales. Average ESs were also computed. Agreement with previous ESs classification was assessed via Cohen's k.

resultsAge and education significantly predicted all MoCA measures except for Orientation, which was related to age only. No sex differences were detected when tested along with age and education. Substantial disagreements with previous ESs classifications were detected. Several items proved to be scarcely sensitive, especially the place item from Orientation and the letter detection task. Memory items showed high discriminative capability, along with certain items assessing executive functions and orientation. DISCUSSION: Item-level information herewith provided for the Italian MoCA can help interpret its scores by Italian practitioners. Italian practitioners should consider an adaptive use of region-specific norms for the MoCA.

Indexed as

Cognitive DysfunctionEducational StatusExecutive FunctionFemaleHumansMaleMental Status and Dementia TestsNeuropsychological TestsPsychometricsAdaptive testingCognitive impairmentCultural differencesItem Response TheoryMontreal Cognitive AssessmentNormative data

Identifiers

PMID34313961
PMCPMC8847194

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.