Evidence map›Paper›PMID 34313542›Full record

ReviewRNA biology2021

RNA modifications act as regulators of cell death.

Lei Xu, Chong Zhang, Hang Yin, Shuai Gong, Nai Wu, Zeqiang Ren, Yi Zhang

Open access · bronzeAbstract readReview
In one paragraph

Review in RNA biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. mCells · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. RNA Modifications Meet Tumors.Cancer management and research · 2022
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lei XuDepartment of General Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Chong ZhangDepartment of General Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Hang Yin
Shuai GongDepartment of General Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Nai WuDepartment of General Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Zeqiang RenDepartment of General Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yi ZhangDepartment of General Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, more than one hundred types of RNA modifications have been found, and many of these modifications are reversible and dynamically regulated. RNA modifications can regulate RNA stability and translation and are thus involved in multiple biological activities. Recently, RNA modifications have been shown to have important roles in the regulation of cell death. Cell death is a critical process that maintains tissue homoeostasis and is regulated by multiple pathways in response to specific stimuli. In this review, we summarize the current understanding of the roles of RNA modifications in cell death mediation and discuss the prospects of such research.

Indexed as

5-MethylcytosineAdenosineAnimalsCell DeathHumansRNA, MessengerRNA Processing, Post-TranscriptionalRNA StabilitySignal Transduction5-hydroxymethylcytosine5-MethylcytosineAdenosineN-methyladenosineRNA, Messengerapoptosisautophagym1Am5Cm6Anecrosis

Identifiers

PMID34313542
PMCPMC8632120
OpenAlexW3186107493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.