Evidence map›Paper›PMID 34313486›Full record

ArticleJournal of feline medicine and surgery2022

Impact of radioiodine treatment on acute phase proteins in hyperthyroid cats.

Katharina Glück, Sabrina Mohrs, Katarina Hazuchova, Natali Bauer, Reto Neiger

Open access · hybridAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Katharina GlückDepartment of Veterinary Clinical Sciences, Small Animal Internal Medicine, Justus-Liebig-Universität Giessen, Germany.ORCID 0000-0003-0371-9144
Sabrina MohrsDepartment of Veterinary Clinical Sciences, Small Animal Internal Medicine, Justus-Liebig-Universität Giessen, Germany.
Katarina HazuchovaDepartment of Veterinary Clinical Sciences, Small Animal Internal Medicine, Justus-Liebig-Universität Giessen, Germany.
Natali BauerDepartment of Veterinary Clinical Sciences, Small Animal Internal Medicine, Justus-Liebig-Universität Giessen, Germany.
Reto NeigerDepartment of Veterinary Clinical Sciences, Small Animal Internal Medicine, Justus-Liebig-Universität Giessen, Germany.
Justus-Liebig-Universität Gießen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to investigate the impact of radioiodine treatment (RIT) on the acute phase proteins (APPs) serum amyloid A (SAA), alpha-1-acid glycoprotein (AGP) and haptoglobin (Hp) in hyperthyroid cats.

methodsBetween June 2013 and November 2014, 33 hyperthyroid cats without clinical or laboratory signs of inflammatory or neoplastic disease and a body weight >2.5 kg were enrolled. Immediately before, and 12, 36, 72 h and 6 days after RIT, serum samples were obtained for determination of APP concentrations.

resultsBoth SAA and AGP concentrations changed significantly after RIT. The concentration of AGP increased gradually after treatment with a maximum concentration at the end of the study period (median baseline 398 μg/ml; median 6 days post-RIT 562 μg/ml [ CONCLUSIONS AND RELEVANCE: RIT induced a mild, mainly not clinically relevant acute phase reaction (APR). AGP and SAA were useful APPs to determine RIT-induced APR.

Indexed as

Cat DiseasesHyperthyroidismAcute-Phase ProteinsAnimalsCatsIodine RadioisotopesOrosomucoidSerum Amyloid A ProteinAcute-Phase ProteinsIodine RadioisotopesOrosomucoidSerum Amyloid A ProteinAcute phase reactionalpha-1-acid glycoproteinendocrineserum amyloid A

Identifiers

PMID34313486
PMCPMC8961241
OpenAlexW3186591173

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.