Evidence map›Paper›PMID 34313462›Full record

ArticlemSystems2021

Identification and Quantification of Bovine Digital Dermatitis-Associated Microbiota across Lesion Stages in Feedlot Beef Cattle.

Ben Caddey, Karin Orsel, Sohail Naushad, Hooman Derakhshani, Jeroen De Buck

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Hoof, Vaginal and Milk Microbiota Alterations in Dairy Cows with Foot Rot.Animals : an open access journal from MDPI · 2026
    Article
  4. Article
  5. Article
  6. Complete genome sequence ofMicrobiology resource announcements · 2025
    Article
  7. Article
  8. Article
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  10. Article
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  15. Article
  16. Journal of pharmacy & bioallied sciences · 2024
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ben CaddeyDepartment of Production Animal Health, Faculty of Veterinary Medicine, University of Calgarygrid.22072.35, Calgary, Alberta, Canada.
Karin OrselDepartment of Production Animal Health, Faculty of Veterinary Medicine, University of Calgarygrid.22072.35, Calgary, Alberta, Canada.
Sohail NaushadOttawa Laboratory Fallowfield, Canadian Food Inspection Agencygrid.418040.9, Ottawa, Ontario, Canada.
Hooman DerakhshaniDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Jeroen De BuckDepartment of Production Animal Health, Faculty of Veterinary Medicine, University of Calgarygrid.22072.35, Calgary, Alberta, Canada.
University of Calgary · CACanadian Food Inspection Agency · CAMcMaster University · CA

Funding

Alberta Agriculture and ForestryCanadian Dairy Commission (CDC)
6 · The paper itself

Abstract

Bovine digital dermatitis (DD) is a skin disorder that is a significant cause of infectious lameness in cattle around the world. However, very little is known about the etiopathogenesis of the disease and the microbiota associated with DD in beef cattle. In this study, we provide a comprehensive characterization of DD and healthy skin microbiota of feedlot beef cattle. We also developed and validated a novel multiplex quantitative PCR (qPCR) assay to quantify the distribution of DD-associated bacterial species across DD lesion stages. We determined the DD-associated microbiota with deep amplicon sequencing of the V3-V4 hypervariable region of the 16S rRNA gene, followed by the application of novel and existing qPCR assays to quantify species distributions of Treponema,

Indexed as

16S metagenomicsbeef cattlebovinedigital dermatitisfeedlothoofmicrobiomeskin microbiotaTreponema

Identifiers

PMID34313462
PMCPMC8409723
OpenAlexW3186103889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.