Evidence map›Paper›PMID 34313225›Full record

ArticleeLife2021

Co-circulation of multiple influenza A reassortants in swine harboring genes from seasonal human and swine influenza viruses.

Pia Ryt-Hansen, Jesper Schak Krog, Solvej Østergaard Breum, Charlotte Kristiane Hjulsager, Anders Gorm Pedersen, Ramona Trebbien, Lars Erik Larsen

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

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  17. The genomic landscape of swine influenza A viruses in Southeast Asia.Proceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Pia Ryt-HansenTechnical University of Denmark, National Veterinary Institute, Lyngby, Denmark.ORCID 0000-0003-4819-6869
Jesper Schak KrogStatens Serum Institut, Copenhagen, Denmark.
Solvej Østergaard BreumStatens Serum Institut, Copenhagen, Denmark.
Charlotte Kristiane HjulsagerStatens Serum Institut, Copenhagen, Denmark.ORCID 0000-0001-7557-8876
Anders Gorm PedersenDepartment of Health Technology, Section for Bioinformatics, Technical University of Denmark, Kongens Lyngby, Denmark.
Ramona TrebbienStatens Serum Institut, Copenhagen, Denmark.
Lars Erik LarsenTechnical University of Denmark, National Veterinary Institute, Lyngby, Denmark.
Statens Serum Institut · DKUniversity of Copenhagen · DKTechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the influenza pandemic in 2009, there has been an increased focus on swine influenza A virus (swIAV) surveillance. This paper describes the results of the surveillance of swIAV in Danish swine from 2011 to 2018. In total, 3800 submissions were received with a steady increase in swIAV-positive submissions, reaching 56% in 2018. Full-genome sequences were obtained from 129 swIAV-positive samples. Altogether, 17 different circulating genotypes were identified including six novel reassortants harboring human seasonal IAV gene segments. The phylogenetic analysis revealed substantial genetic drift and also evidence of positive selection occurring mainly in antigenic sites of the hemagglutinin protein and confirmed the presence of a swine divergent cluster among the H1pdm09Nx (clade 1A.3.3.2) viruses. The results provide essential data for the control of swIAV in pigs and emphasize the importance of contemporary surveillance for discovering novel swIAV strains posing a potential threat to the human population.

Indexed as

Genetic VariationAnimalsDenmarkGenetic DriftGenotypeHemagglutination Inhibition TestsHumansInfluenza A virusInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H1N2 SubtypeInfluenza A Virus, H3N2 SubtypeMutationNeuraminidaseOrthomyxoviridae InfectionsPhylogenyReassortant VirusesNeuraminidaseRNA, Viralinfectious diseaseinfluenza A virusmicrobiologyswineviral driftviral shiftviruszoonotic potential

Identifiers

PMID34313225
PMCPMC8397370
OpenAlexW3185344063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.