Evidence map›Paper›PMID 34313011›Full record

ArticleJournal of diabetes investigation2022

Prevalence and clinical characteristics of fulminant type 1 diabetes mellitus in Korean adults: A multi-institutional joint research.

Sun Ok Song, Jae-Seung Yun, Seung-Hyun Ko, Yu-Bae Ahn, Bo-Yeon Kim, Chul-Hee Kim, Ja Young Jeon, Dae Jung Kim, Da Hae Seo, So Hun Kim and 5 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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  5. Associations between Diabetes, Diabetes Duration, and Psychiatric Difficulties: A Nationwide Cross-sectional Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 2 countries.

Sun Ok SongDivision of Endocrinology and Metabolism, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0003-4829-3407
Jae-Seung YunDivision of Endocrinology and Metabolism, Department of Internal Medicine, St. Vincent's Hospital, The Catholic University College of Medicine, Seoul, Korea.
Seung-Hyun KoDivision of Endocrinology and Metabolism, Department of Internal Medicine, St. Vincent's Hospital, The Catholic University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3703-1479
Yu-Bae AhnDivision of Endocrinology and Metabolism, Department of Internal Medicine, St. Vincent's Hospital, The Catholic University College of Medicine, Seoul, Korea.
Bo-Yeon KimDivision of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Korea.
Chul-Hee KimDivision of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Korea.
Ja Young JeonDepartment of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0002-3877-0479
Dae Jung KimDepartment of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0003-1025-2044
Da Hae SeoDivision of Endocrinology and Metabolism, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.
So Hun KimDivision of Endocrinology and Metabolism, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.ORCID https://orcid.org/0000-0002-2554-3664
Jung Hyun NohDivision of Endocrinology and Metabolism, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Da Young LeeDivision of Endocrinology and Metabolism, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.
Kyung-Soo KimDivision of Endocrinology and Metabolism, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.ORCID https://orcid.org/0000-0002-7738-2284
Soo-Kyung KimDivision of Endocrinology and Metabolism, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.ORCID https://orcid.org/0000-0002-2601-3438
Type 1 Diabetes Study Group of Gyeonggi-Incheon Branch of the Korean Diabetes Association
CHA University Bundang Medical Center · KRThe Catholic University of Korea St. Vincent's Hospital · KRAjou University · KRSoonchunhyang University · KRAnsan University · KRInha University Hospital · KRInje University Ilsan Paik Hospital · KRKorea University · KRNational Health Insurance Service Ilsan Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionWe aimed to determine the hospital-based prevalence and clinical features of fulminant type 1 diabetes mellitus in Korea. MATERIALS AND

methodsWe identified all patients with diabetes who regularly visited the Endocrinology outpatient clinics at eight centers for a period >1 year between January 2012 and June 2017. We investigated their medical records retrospectively.

resultsDuring this period, 76,309 patients with diabetes had been regularly followed up. Among them, 913 (1.2%) patients had type 1 diabetes mellitus . There were 462 patients with type 1 diabetes mellitus whose data at the time of the first diagnosis could be identified (359 and 103 with non-ketosis and ketosis onset, respectively). Of these, 15 (3.2% of type 1 diabetes mellitus, 14.6% of ketosis onset diabetes) patients had fulminant type 1 diabetes mellitus. The median ages at diagnosis were 40 and 27 years in the fulminant type 1 diabetes mellitus and non-fulminant type 1 diabetes mellitus groups, respectively. The patients with fulminant type 1 diabetes mellitus had higher body mass index, lower glycated hemoglobin and fasting/peak C-peptide, and lower frequent glutamic acid decarboxylase antibody-positive rate (P =0.0010) at diagnosis. Furthermore, they had lower glycated hemoglobin at the last follow-up examination than those with non-fulminant type 1 diabetes mellitus.

conclusionsIn this study, the prevalence of type 1 diabetes mellitus was 1.2% among all patients with diabetes, and that of fulminant type 1 diabetes mellitus was 3.2% among those newly diagnosed with type 1 diabetes mellitus. The glycated hemoglobin levels were lower in patients with fulminant type 1 diabetes mellitus than in those with non-fulminant type 1 diabetes mellitus at diagnosis and at the last follow-up examination.

Indexed as

AdultAsian PeopleAutoantibodiesBody Mass IndexC-PeptideDiabetes Mellitus, Type 1Diabetic KetoacidosisFemaleGlutamate DecarboxylaseGlycated HemoglobinHumansMaleMiddle AgedPrevalenceRepublic of KoreaRetrospective StudiesAutoantibodiesC-PeptideGlutamate DecarboxylaseGlycated HemoglobinFulminant type 1 diabetes mellitusKoreaPrevalence

Identifiers

PMID34313011
PMCPMC8756324
OpenAlexW3186360829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.