Evidence map›Paper›PMID 34312991›Full record

ArticleEmergency medicine Australasia : EMA2021

Outcomes for emergency department patients with suspected and confirmed COVID-19: An analysis of the Australian experience in 2020 (COVED-5).

Gerard M O'Reilly, Rob D Mitchell, Biswadev Mitra, Hamed Akhlaghi, Viet Tran, Jeremy S Furyk, Paul Buntine, Anselm Wong, Vinay Gangathimmaiah, Jonathan Knott and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in Emergency medicine Australasia : EMA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 12 institutions in 1 country.

Gerard M O'ReillyEmergency and Trauma Centre, Alfred Health, Melbourne, Victoria, Australia.ORCID 0000-0001-5763-917X
Rob D MitchellEmergency and Trauma Centre, Alfred Health, Melbourne, Victoria, Australia.ORCID 0000-0002-6422-3348
Biswadev MitraEmergency and Trauma Centre, Alfred Health, Melbourne, Victoria, Australia.ORCID 0000-0002-0508-2450
Hamed AkhlaghiEmergency Department, St Vincent's Hospital, Melbourne, Victoria, Australia.ORCID 0000-0002-3929-7265
Viet TranEmergency Department, Royal Hobart Hospital, Hobart, Tasmania, Australia.ORCID 0000-0002-8890-1457
Jeremy S FurykEmergency Department, Barwon Health, Geelong, Victoria, Australia.ORCID 0000-0002-9503-0928
Paul BuntineEmergency Department, Eastern Health, Melbourne, Victoria, Australia.
Anselm WongEmergency Department, Austin Hospital, Melbourne, Victoria, Australia.ORCID 0000-0002-6817-7289
Vinay GangathimmaiahEmergency Department, Townsville University Hospital, Townsville, Queensland, Australia.
Jonathan KnottDepartment of Critical Care, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0003-1503-0440
Allison MooreEmergency Department, Sutherland Hospital, Sydney, New South Wales, Australia.
Jung Ro AhnCentral Clinical School, Monash University, Melbourne, Victoria, Australia.
Quillan ChanCentral Clinical School, Monash University, Melbourne, Victoria, Australia.
Andrew WangCentral Clinical School, Monash University, Melbourne, Victoria, Australia.
Han GohEmergency Department, St Vincent's Hospital, Melbourne, Victoria, Australia.
Ashley LoughmanEmergency Department, Royal Hobart Hospital, Hobart, Tasmania, Australia.
Nicole LowryEmergency Department, Barwon Health, Geelong, Victoria, Australia.
Liam HackettEmergency Department, Eastern Health, Melbourne, Victoria, Australia.
Muhuntha Sri-GaneshanEmergency Department, Austin Hospital, Melbourne, Victoria, Australia.
Nicole ChapmanEmergency Department, Townsville University Hospital, Townsville, Queensland, Australia.
Maximilian RaosEmergency Department, Sutherland Hospital, Sydney, New South Wales, Australia.
Michael P NoonanEmergency and Trauma Centre, Alfred Health, Melbourne, Victoria, Australia.
De Villiers SmitEmergency and Trauma Centre, Alfred Health, Melbourne, Victoria, Australia.
Peter A CameronEmergency and Trauma Centre, Alfred Health, Melbourne, Victoria, Australia.ORCID 0000-0002-1443-557X
COVED Project Team
National Trauma Research Institute · AUMonash University · AUAlfred Health · AUBarwon Health · AUEastern Health · AUSutherland Hospital · AUThe University of Melbourne · AUTownsville Hospital · AUUniversity of Tasmania · AUAustin Hospital · AUSt Vincent's Hospital Melbourne · AUThe Royal Melbourne Hospital · AU

Funding

MRFF 1159907MRFF MRF1139686National Health and Medical Research Council GNT1142691National Health and Medical Research Council ID1159907Study, Education and Research Trust Account of Townsville Hospital and Health Service Research Grant
6 · The paper itself

Abstract

objectiveThe aim of the present study was to describe the characteristics and outcomes of patients presenting to Australian EDs with suspected and confirmed COVID-19 during 2020, and to determine the predictors of in-hospital death for SARS-CoV-2 positive patients.

methodsThis analysis from the COVED Project presents data from 12 sites across four Australian states for the period from 1 April to 30 November 2020. All adult patients who met local criteria for suspected COVID-19 and underwent testing for SARS-CoV-2 in the ED were eligible for inclusion. Study outcomes were mechanical ventilation and in-hospital mortality.

resultsAmong 24 405 eligible ED presentations over the whole study period, 423 tested positive for SARS-CoV-2. During the 'second wave' from 1 July to 30 September 2020, 26 (6%) of 406 SARS-CoV-2 patients received invasive mechanical ventilation, compared to 175 (2%) of the 9024 SARS-CoV-2 negative patients (odds ratio [OR] 3.5; 95% confidence interval [CI] 2.3-5.2, P < 0.001), and 41 (10%) SARS-CoV-2 positive patients died in hospital compared to 312 (3%) SARS-CoV-2 negative patients (OR 3.2; 95% CI 2.2-4.4, P = 0.001). For SARS-CoV-2 positive patients, the strongest independent predictors of hospital death were age (OR 1.1; 95% CI 1.1-1.1, P < 0.001), higher triage category (OR 3.5; 95% CI 1.3-9.4, P = 0.012), obesity (OR 4.2; 95% CI 1.2-14.3, P = 0.024) and receiving immunosuppressive treatment (OR 8.2; 95% CI 1.8-36.7, P = 0.006).

conclusionsED patients who tested positive for SARS-CoV-2 had higher odds of mechanical ventilation and death in hospital. The strongest predictors of death were age, a higher triage category, obesity and receiving immunosuppressive treatment.

Indexed as

COVID-19AdultAustraliaEmergency Service, HospitalHospital MortalityHumansSARS-CoV-2COVID-19emergencyisolationquality improvementregistry

Identifiers

PMID34312991
PMCPMC8420351
OpenAlexW3184802182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.