Evidence map›Paper›PMID 34312832›Full record

ArticleCardiology journal2023

The impact of transcatheter aortic valve implantation planning and procedure on acute and chronic renal failure.

Markus Jäckel, Simon Keller, Eric Peter Prager, Dawid Leander Staudacher, Christopher Schlett, Manfred Zehender, Fabian Bamberg, Christoph Bode, Constantin von Zur Mühlen, Peter Stachon

Open access · goldAbstract read
In one paragraph

Article in Cardiology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Observational
  7. Review
  8. Article
  9. Chronic kidney disease and transcatheter aortic valve implantation.Cardiovascular intervention and therapeutics · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Markus JäckelDepartment of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany. markus.jaeckel@uniklinik-freiburg.de.ORCID 0000-0001-8638-5228
Simon KellerDepartment of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany.
Eric Peter PragerDepartment of Nephrology, University Hospital Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Dawid Leander StaudacherDepartment of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany.
Christopher SchlettDepartment of Diagnostic and Interventional Radiology, Medical Center - Faculty of Medicine, University of Freiburg, Germany.
Manfred ZehenderDepartment of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany.
Fabian BambergDepartment of Diagnostic and Interventional Radiology, Medical Center - Faculty of Medicine, University of Freiburg, Germany.
Christoph BodeDepartment of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany.
Constantin von Zur MühlenDepartment of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany.
Peter StachonDepartment of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany.
University of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere aortic valve stenosis inhibits renal perfusion, thereby potentially worsening renal function, in particular in elderly patients most often assigned to transcatheter aortic valve implantation (TAVI). Pre-TAVI diagnostics and the procedure itself may adversely impact renal function, however renal perfusion and function may also improve post-procedure. This study aimed to clarify the impact of TAVI planning and procedure on kidney function

methodsIn this retrospective study, kidney function of patients who underwent transfemoral TAVI at a tertiary university hospital between 2016 and 2019 was analyzed. The present study investigated kidney function at baseline, after computed tomography (CT) was performed for evaluation of TAVI, after TAVI, at discharge and at follow-up.

resultsAmong 366 patients, the prevalence of acute kidney injury (AKI) was 14.5% after TAVI. Independent predictors of AKI were arterial hypertension, baseline creatinine, AKI post CT and coronary intervention during pre-procedural diagnostics. At discharge and follow-up, 2.1% and 3.4%, respectively had sustained relevant impairment of kidney function (defined as creatinine/baseline creatinine > 1.5 or renal replacement therapy). Patients with known chronic kidney disease showed no higher rates of short- and long-term impairment, but higher rates of improvement of renal function after TAVI.

conclusionsIn most cases TAVI does not worsen renal function. A sustained impairment after TAVI was found in only a few cases. This was independent of reduced baseline kidney function. Transfemoral TAVI can thus be planned and performed even in patients with higher stages of chronic kidney disease.

Indexed as

Acute Kidney InjuryAortic Valve StenosisKidney Failure, ChronicRenal Insufficiency, ChronicTranscatheter Aortic Valve ReplacementAgedAortic ValveCreatinineHumansRetrospective StudiesRisk FactorsTreatment OutcomeCreatinineacute kidney failurecomputed tomographykidney functiontranscatheter aortic valve implantation

Identifiers

PMID34312832
PMCPMC10129259
OpenAlexW3167646635

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.