Evidence map›Paper›PMID 34312744›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2021

Host-pathogen interaction between macrophage co-cultures with Staphylococcus aureus biofilms.

Julio E Arce Miranda, José L Baronetti, Ma Gabriela Paraje

Abstract read
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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Julio E Arce MirandaIMBIV-National Scientific and Technical Research Council (CONICET), Av. Vélez Sarsfield 299, X5000HUA, Córdoba, Argentina.
José L BaronettiIMBIV-National Scientific and Technical Research Council (CONICET), Av. Vélez Sarsfield 299, X5000HUA, Córdoba, Argentina.
Ma Gabriela ParajeIMBIV-National Scientific and Technical Research Council (CONICET), Av. Vélez Sarsfield 299, X5000HUA, Córdoba, Argentina. gabrielaparaje@gmail.com.
Instituto Multidisciplinario de Biología Vegetal · ARCordoba University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of Staphylococcus aureus to form biofilms is an important virulence factor. During the infectious process, the interaction between biofilms and immune cells is determinant; however, the properties that make biofilms resistant to the immune system are not well characterized. In order to better understand this, we evaluated the in vitro interaction of macrophages during the early stages of S. aureus biofilm formation. Biofilm formation was evaluated by crystal violet staining, light microscopy, and confocal scanning laser microscopy. Furthermore, different activation on L-arginine pathways such as nitric oxide (NO

Indexed as

BiofilmsCoculture TechniquesHost-Pathogen InteractionsHumansInterleukin-6MacrophagesReactive Oxygen SpeciesStaphylococcal InfectionsStaphylococcus aureusInterleukin-6Reactive Oxygen SpeciesBiofilmsL-arginine pathwayMacrophagesOxidative/nitrosative stressStaphylococcus aureus

Identifiers

PMID34312744
OpenAlexW3184865563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.