ReviewThe Journal of antimicrobial chemotherapy2021
Change-points in antibiotic consumption in the community, European Union/European Economic Area, 1997-2017.
Review in The Journal of antimicrobial chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Overview of Methods for Assessing Antimicrobial Use in Outpatient Settings in High-Income Countries: A Narrative Review.Antibiotics (Basel, Switzerland) · 2025Review
- Impact of a multifaceted intervention programme on antibiotic prescribing and dispensing in four patient-centred settings in five European countries. The HAPPY PATIENT project.Family practice · 2025Article
- Effects of a Primary Care Antimicrobial Stewardship Program on Meticillin-ResistantAntibiotics (Basel, Switzerland) · 2024Article
- How Did COVID-19 Impact the Antimicrobial Consumption and Bacterial Resistance Profiles in Brazil?Antibiotics (Basel, Switzerland) · 2023Article
- Prediction of tsunami of resistance to some antibiotics is not far-fetched which used during COVID-19 pandemic.Journal of clinical laboratory analysis · 2023Review
- Health alliance for prudent prescribing and yield of antibiotics in a patient-centred perspective (HAPPY PATIENT): a before-and-after intervention and implementation study protocol.BMC primary care · 2022Article
- Antibiotic use during pregnancy and the risk of preterm birth: a population-based Swedish cohort study.The Journal of antimicrobial chemotherapy · 2022Article
- Inappropriate Antibiotic Use in Zimbabwe in the COVID-19 Era: A Perfect Recipe for Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2022Article
- Antimicrobial Stewardship in Surgery: A Literature Bibliometric Analysis.Frontiers in public health · 2022Article
- Quality appraisal of antibiotic consumption in the community, European Union/European Economic Area, 2009 and 2017.The Journal of antimicrobial chemotherapy · 2021Article
- Consumption of penicillins in the community, European Union/European Economic Area, 1997-2017.The Journal of antimicrobial chemotherapy · 2021Review
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSurveillance of antibiotic consumption in the community is of utmost importance to inform and evaluate control strategies. Data on two decades of antibiotic consumption in the community were collected from 30 EU/European Economic Area (EEA) countries. This article reviews temporal trends and the presence of abrupt changes in subgroups of relevance in antimicrobial stewardship.
methodsFor the period 1997-2017, data on yearly antibiotic consumption in the community, aggregated at the level of the active substance, were collected using the WHO ATC classification and expressed in DDD (ATC/DDD index 2019) per 1000 inhabitants per day. We applied a range of non-linear mixed models to assess the presence of changes in the consumption of antibacterials for systemic use (ATC group J01) and eight antibiotic subgroups.
resultsFor the majority of the studied groups, a country-specific change-point model provided the best fit. Depending on the antibiotic group/subgroup and on the country, change-points were spread out between 2000 and 2013.
conclusionsDue to the heterogeneity in antibiotic consumption in the community across EU/EEA countries, a country-specific change-point model provided the better fit. Given the limitations of this model, our recommendation for the included countries is to carefully interpret the country-specific results presented in this article and to use the tutorial included in this series to conduct their own change-point analysis when evaluating the impact of changes in regulations, public awareness campaigns, and other national interventions to improve antibiotic consumption in the community.
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