Evidence map›Paper›PMID 34312611›Full record

ArticleNature computational science2021

A survival model generalized to regression learning algorithms.

Yuanfang Guan, Hongyang Li, Daiyao Yi, Dongdong Zhang, Changchang Yin, Keyu Li, Ping Zhang

Abstract read
In one paragraph

Article in Nature computational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Reduction techniques for survival analysis.Lifetime data analysis · 2026
    Article
  2. SepsisCalc: Integrating Clinical Calculators into Early Sepsis Prediction via Dynamic Temporal Graph Construction.KDD : proceedings. International Conference on Knowledge Discovery & Data Mining · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Multilevel Modeling of Joint Damage in Rheumatoid Arthritis.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuanfang GuanDepartment of Computational Medicine and Bioinformatics, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-8275-2852
Hongyang LiDepartment of Computational Medicine and Bioinformatics, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
Daiyao YiDepartment of Biomedical Engineering, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
Dongdong ZhangDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Changchang YinDepartment of Computer Science and Engineering, The Ohio State University, Columbus, OH, USA.
Keyu LiDepartment of Computational Medicine and Bioinformatics, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
Ping ZhangDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-4601-0779

Funding

Machine Learning for Drug Response PredictionR35GM133346 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Yuanfang Guan · 2019 to 2026
$3.2M
NIGMS NIH HHS R35 GM133346
6 · The paper itself

Abstract

Survival prediction is an important problem that is encountered widely in industry and medicine. Despite the explosion of artificial intelligence technologies, no uniformed method allows the application of any type of regression learning algorithm to a survival prediction problem. Here, we present a statistical modeling method that is generalized to all types of regression learning algorithm, including deep learning. We present its empirical advantage when it is applied to traditional survival problems. We demonstrate its expanded applications in different types of regression learning algorithm, such as gradient boosted trees, convolutional neural networks and recurrent neural networks. Additionally, we demonstrate its application in clinical informatic data, pathological images and the hardware industry. We expect that this algorithm will be widely applicable for diverse types of survival data, including discrete data types and those suitable for deep learning such as those with time or spatial continuity.

Identifiers

PMID34312611
PMCPMC8303029

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.