Evidence map›Paper›PMID 34312463›Full record

ArticleScientific reports2021

Classification of glioblastoma versus primary central nervous system lymphoma using convolutional neural networks.

Malia McAvoy, Paola Calvachi Prieto, Jakub R Kaczmarzyk, Iván Sánchez Fernández, Jack McNulty, Timothy Smith, Kun-Hsing Yu, William B Gormley, Omar Arnaout

Abstract readComparative StudyValidation Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Malia McAvoy *Department of Neurosurgery, University of Washington, Ninth & Jefferson Building, 908 Jefferson St., Fifth Floor, Seattle, WA, 98104, USA. maliam4@uw.edu.ORCID 0000-0002-9998-4737
Paola Calvachi Prieto *Department of Neurosurgery, Computational Neuroscience Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-5356-0130
Jakub R KaczmarzykMedical Scientist Training Program, Stony Brook University School of Medicine, Stony Brook, NY, USA.ORCID 0000-0002-5544-7577
Iván Sánchez FernándezDivision of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-4313-002X
Jack McNultyColumbia Vagelos College of Physicians and Surgeons, New York, NY, USA.
Timothy SmithDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Kun-Hsing YuDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-9892-8218
William B GormleyDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Omar ArnaoutDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Funding

Resource DiscoveryP41EB019936 · NIBIB · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI David Nelson Kennedy · 2016 to 2026
$15.2M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008444 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI FROHMAN, MICHAEL A. · 1992 to 2024
$12.6M
Nipype: Dataflows for Reproducible Biomedical ResearchR01EB020740 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GHOSH, SATRAJIT SUJIT · 2016 to 2019
$2.7M
NIBIB NIH HHS P41 EB019936NIBIB NIH HHS R01 EB020740NIGMS NIH HHS T32 GM008444
6 · The paper itself

Abstract

A subset of primary central nervous system lymphomas (PCNSL) are difficult to distinguish from glioblastoma multiforme (GBM) on magnetic resonance imaging (MRI). We developed a convolutional neural network (CNN) to distinguish these tumors on contrast-enhanced T

Indexed as

Magnetic Resonance ImagingNeural Networks, ComputerAdultAgedAged, 80 and overBrain NeoplasmsDiagnosis, DifferentialFemaleGlioblastomaHumansLymphomaMachine LearningMaleMiddle AgedYoung Adult

Identifiers

PMID34312463
PMCPMC8313677

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.