ArticleScientific reports2021
Relationship between abnormalities detected by magnetic resonance imaging and knee symptoms in early knee osteoarthritis.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Association between body composition, knee synovial effusion, and serum glutamate in middle-aged women with knee osteoarthritis: a cross-sectional study.Scientific reports · 2026Article
- Synovial Fluid Characteristics and Pain Recovery Trajectory Following Rehabilitation in Patients with Meniscal Tears: A Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
- Progress in machine learning-assisted medical imaging for osteoarthritis and osteoporosis diagnosis: a narrative review.Quantitative imaging in medicine and surgery · 2026Review
- Associations of clinical measures and structural knee magnetic resonance imaging findings with knee symptoms in a birth cohort of 33-year-old adults.Osteoarthritis and cartilage open · 2026Article
- Mechanisms of pain occurrence in osteoarthritis: peripheral triggers, sensitization, and the path to persistence.Frontiers in immunology · 2026Review
- Ultrasound therapy inhibits knee osteoarthritis progression in rabbits by activating the PPARs pathway: a pilot study.Annals of medicine · 2025Article
- Rehabilitation of the Knee After Autologous Matrix-Induced Chondrogenesis: A Systematic Review of Rehabilitation Protocols and Clinical and Radiological Outcomes.Orthopaedic journal of sports medicine · 2025Review
- Imaging-based measures of synovitis in knee osteoarthritis: A scoping review and narrative synthesis.Osteoarthritis and cartilage open · 2025Review
- Knee Pain Expansion in Early Osteoarthritis: Findings from Iwaki Cohort Study.Journal of pain research · 2025Article
- Genicular Artery embolisation in Patients with Osteoarthritis of the Knee (GENESIS) Using Permanent Microspheres: Long-Term Results.Cardiovascular and interventional radiology · 2024Article
- Assessing the Value of Imaging Data in Machine Learning Models to Predict Patient-Reported Outcome Measures in Knee Osteoarthritis Patients.Bioengineering (Basel, Switzerland) · 2024Article
- Association between knee magnetic resonance imaging markers and knee symptoms over 6-9 years in young adults.Rheumatology (Oxford, England) · 2024Article
- Investigating the relationship between body structure status, work activity type, and the prevalence of musculoskeletal disorders among detergent industry workers.Work (Reading, Mass.) · 2024Article
- Greater medial proximal tibial slope is associated with bone marrow lesions in middle-aged women with early knee osteoarthritis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2023Article
- Association between bone marrow lesions and bone mineral density of the proximal tibia in end-stage osteoarthritic knees.Scientific reports · 2023Article
- Subchondral Bone Cyst Development in Osteoarthritis: From Pathophysiology to Bone Microarchitecture Changes and Clinical Implementations.Journal of clinical medicine · 2023Review
- Effusion detected by ultrasonography and overweight may predict the risk of knee osteoarthritis in females with early knee osteoarthritis: a retrospective analysis of Iwaki cohort data.BMC musculoskeletal disorders · 2022Article
- Role of imaging in surgical decision making in young knee osteoarthrosis.European journal of radiology open · 2022Article
- Multimodal Magnetic Resonance Imaging to Diagnose Knee Osteoarthritis under Artificial Intelligence.Computational intelligence and neuroscience · 2022Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the prevalence of magnetic resonance imaging (MRI) findings and their relationship with knee symptoms in women without radiographic evidence of knee osteoarthritis (KOA). This cross-sectional cohort study included 359 Japanese women without radiographic evidence of KOA (Kellgren‒Lawrence grade < 2). All participants underwent T2-weighted fat-suppressed MRI of their knees. Structural abnormalities (cartilage damage, bone marrow lesions [BMLs], subchondral cysts, bone attrition, osteophytes, meniscal lesions, and synovitis) were scored according to the whole-organ MRI score method. Knee symptoms were evaluated using the Knee Injury and Osteoarthritis Outcome Score. Participants were divided into early and non-KOA groups based on early KOA classification criteria. Logistic regression analysis was performed to evaluate the relationship between MRI abnormalities and knee symptoms. Cartilage damage was the most common abnormality (43.5%). The prevalences of cartilage damage, BMLs, subchondral cysts, bone attrition, meniscal lesions, and synovitis were higher in patients with early KOA than in those without. Synovitis (odds ratio [OR] 2.254, P = 0.002) and meniscal lesions (OR 1.479, P = 0.031) were positively associated with the presence of early KOA. Synovitis was most strongly associated with knee pain and might be a therapeutic target in patients with early KOA.
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