Evidence map›Paper›PMID 34312246›Full record

ReviewCold Spring Harbor perspectives in biology2022

3D or Not 3D: Shaping the Genome during Development.

Juliane Glaser, Stefan Mundlos

Open access · greenAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Chromosomal Instability and Chromoanagenesis as Forces for Genomic Evolution.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  4. Article
  5. Epigenetic insights into Fragile X Syndrome.Frontiers in cell and developmental biology · 2024
    Review
  6. Article
  7. Article
  8. Function and Evolution of the Loop Extrusion Machinery in Animals.International journal of molecular sciences · 2023
    Review
  9. Epigenetics of pregnancy: looking beyond the DNA code.Journal of assisted reproduction and genetics · 2022
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Juliane GlaserRG Development and Disease, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.
Stefan MundlosRG Development and Disease, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.
Max Planck Institute for Molecular Genetics · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most fundamental questions in developmental biology is how one fertilized cell can give rise to a fully mature organism and how gene regulation governs this process. Precise spatiotemporal gene expression is required for development and is believed to be achieved through a complex interplay of sequence-specific information, epigenetic modifications,

Indexed as

Epigenesis, GeneticGene Expression RegulationChromatinDNA Transposable ElementsEmbryo, MammalianChromatinDNA Transposable Elements

Identifiers

PMID34312246
PMCPMC9159266
OpenAlexW3185416165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.