Evidence map›Paper›PMID 34312215›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2021

A Grant-Based Experiment to Train Clinical Investigators: The AACR/ASCO Methods in Clinical Cancer Research Workshop.

Daniel D Von Hoff, Gary M Clark, Charles A Coltman, Mary L Disis, S G Eckhardt, Lee M Ellis, Margaret Foti, Elizabeth Garrett-Mayer, Mithat Gönen, Manuel Hidalgo and 16 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 20 institutions in 2 countries.

Daniel D Von HoffTranslational Genomics Research Institute, Phoenix, Arizona. dvh@tgen.org.ORCID 0000-0003-4723-7681
Gary M ClarkGary Clark Statistical Consulting LLC, Superior, Colorado.
Charles A Coltman
Mary L DisisUW Medicine Cancer Vaccine Institute, University of Washington, Seattle, Washington.
S G EckhardtThe University of Texas at Austin, Dell Medical School, Austin, Texas.
Lee M EllisThe University of Texas MD Anderson Cancer Center, Houston, Texas.
Margaret FotiAmerican Association for Cancer Research, Philadelphia, Pennsylvania.
Elizabeth Garrett-MayerAmerican Society of Clinical Oncology, Alexandria, Virginia.ORCID 0000-0003-4709-0333
Mithat GönenMemorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-8683-8477
Manuel HidalgoWeill Cornell Medicine, New York Presbyterian Hospital, New York, New York.
Susan G HilsenbeckDan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-7962-673X
John H Littlefield
Patricia M LoRussoYale University, Yale Cancer Center, New Haven, Connecticut.
H Kim LyerlyDuke University, Durham, North Carolina.ORCID 0000-0002-0063-4770
Neal J MeropolFlatiron Health, New York, New York.
Jyoti D PatelNorthwestern University, Chicago, Illinois.
Steven PiantadosiDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-4409-9896
Dean A PostAmerican Association for Cancer Research, Philadelphia, Pennsylvania.ORCID 0000-0003-2745-4312
Meredith M ReganDana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0002-2428-6109
Yu ShyrVanderbilt University Medical Center, Nashville, Tennessee.
Margaret A TemperoUniversity of California San Francisco Pancreas Center, San Francisco, California.ORCID 0000-0002-2777-9208
Joel E TepperUniversity of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina.ORCID 0000-0002-8591-4228
Jamie Von RoennAmerican Society of Clinical Oncology, Alexandria, Virginia.
Louis M WeinerGeorgetown Lombardi Comprehensive Cancer Center, Washington, D.C.ORCID 0000-0001-5192-0710
Donn C YoungThe Ohio State University Comprehensive Cancer Center, Columbus, Ohio.
Nu V VuUniversity of Geneva Faculty of Medicine, Geneva, Switzerland.
Translational Genomics Research Institute · USAmerican Association For Cancer Research · USAmerican Society of Clinical Oncology · USBrigham and Women's Hospital · USChildren's Cancer Center · USDana-Farber Cancer Institute · USDuke University · USFlatiron Health (United States) · USGeorgetown University Medical Center · USInfectious Disease Research Institute · USMemorial Sloan Kettering Cancer Center · USMidwestern University · USNewYork–Presbyterian Hospital · USStatistical Research (United States) · USThe Ohio State University · USThe University of Texas at Austin · USThe University of Texas MD Anderson Cancer Center · USUniversity of California, San Francisco · USUniversity of Geneva · CHUniversity of North Carolina at Chapel Hill · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Workshop on Methods in Clinical Cancer ResearchR25CA068647 · NCI · AMERICAN ASSOCIATION FOR CANCER RESEARCH · PI HIDALGO, MANUEL · 1996 to 2023
$5.1M
NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA008748NCI NIH HHS R25 CA068647
6 · The paper itself

Abstract

To address the need for clinical investigators in oncology, American Association for Cancer Research (AACR) and American Society for Clinical Oncology (ASCO) established the Methods in Clinical Cancer Research Workshop (MCCRW). The workshop's objectives were to: (i) provide training in the methods, design, and conduct of clinical trials; (ii) ensure that clinical trials met federal and international ethical guidelines; (iii) evaluate the effectiveness of the workshop; and (iv) create networking opportunities for young investigators with mentoring senior faculty. Educational methods included: (i) didactic lectures, (ii) Small Group Discussion Sessions, (iii) Protocol Development Groups, and (iv) one-on-one mentoring. Learning focused on the development of an Institutional Review Board (IRB)-ready protocol, which was submitted on the last day of the workshop. Evaluation methods included: (i) pre- and postworkshop tests, (ii) students' workshop evaluations, (iii) faculty's ratings of protocol development, (iv) students' productivity in clinical research after the workshop, and (v) an independent assessment of the workshop. From 1996 to 2014, 1,932 students from diverse backgrounds attended the workshop. There was a significant improvement in the students' level of knowledge from the pre- to the postworkshop exams (

Indexed as

Financing, OrganizedMedical OncologyNeoplasmsSocieties, MedicalBiomedical ResearchHumansResearch PersonnelUnited States

Identifiers

PMID34312215
PMCPMC8530870
OpenAlexW3184308496

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.