Evidence map›Paper›PMID 34312089›Full record

ReviewAnimal : an international journal of animal bioscience2021

Review: Livestock disease resilience: from individual to herd level.

A Doeschl-Wilson, P W Knap, T Opriessnig, S J More

Abstract readReview
In one paragraph

Review in Animal : an international journal of animal bioscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Article
  7. Review
  8. Article
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  15. Application of Genomic Selection in Beef Cattle Disease Prevention.Animals : an open access journal from MDPI · 2025
    Review
  16. Article
  17. Selection for Resilience in Livestock Production Systems.International journal of molecular sciences · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A Doeschl-WilsonThe Roslin Institute, University of Edinburgh, Roslin Institute Building, Easter Bush EH25 9RG, Scotland, UK. Electronic address: andrea.wilson@roslin.ed.ac.uk.
P W KnapGenus-PIC, 24837 Schleswig, Germany.
T OpriessnigThe Roslin Institute, University of Edinburgh, Roslin Institute Building, Easter Bush EH25 9RG, Scotland, UK.
S J MoreCentre for Veterinary Epidemiology and Risk Analysis, School of Veterinary Medicine, University College Dublin, Veterinary Science Centre Belfield, Dublin D04 W6F6, Ireland.

Funding

Biotechnology and Biological Sciences Research Council BB/T004401/1
6 · The paper itself

Abstract

Infectious diseases are a major threat to the sustainable production of high-producing animals. Control efforts, such as vaccination or breeding approaches often target improvements to individual resilience to infections, i.e., they strengthen an animal's ability to cope with infection, rather than preventing infection per se. There is increasing evidence for the contribution of non-clinical carriers (animals that become infected and are infectious but do not develop clinical signs) to the overall health and production of livestock populations for a wide range of infectious diseases. Therefore, we strongly advocate a shift of focus from increasing the disease resilience of individual animals to herd disease resilience as the appropriate target for sustainable disease control in livestock. Herd disease resilience not only captures the direct effects of vaccination or host genetics on the health and production performance of individuals but also the indirect effects on the environmental pathogen load that herd members are exposed to. For diseases primarily caused by infectious pathogens shed by herd members, these indirect effects on herd resilience are mediated both by individual susceptibility to infection and by characteristics (magnitude of infectiousness, duration of infectious period) that influence pathogen shedding from infected individuals. We review what is currently known about how vaccination and selective breeding affect herd disease resilience and its underlying components, and outline the changes required for improvement. To this purpose, we also seek to clarify and harmonise the terminology used in the different animal science disciplines to facilitate future collaborative approaches to infectious disease control in livestock.

Indexed as

LivestockSelective BreedingAnimalsVaccinationBreedingDisease resistanceDisease transmissionInfectious diseaseVaccination

Identifiers

PMID34312089
PMCPMC8664713

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.