ReviewNeurological research and practice2021
Neurological manifestations of COVID-19 - an approach to categories of pathology.
Review in Neurological research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Electrophysiological assessment in patients with COVID-19-related peripheral neuropathies and myopathies: a systematic review.Journal of neurophysiology · 2023Pooled it
- Review
- Need for awareness and surveillance of long-term post-COVID neurodegenerative disorders. A position paper from the neuroCOVID-19 task force of the European Academy of Neurology.Journal of neurology · 2025Review
- Article
- Acute transverse myelitis (ATM) associated with COVID 19 infection and vaccination: A case report and literature review.AIMS neuroscience · 2024Article
- Article
- Review
- Article
- Impact of new-onset and preexisting neurological disorders in COVID-19 patients.Brain and behavior · 2023Article
- A Case Report of an Atypical Neurological Presentation of COVID-19 in Pregnancy.Anesthesiology and pain medicine · 2023Article
- [Neurointensive care medicine and COVID-19].Der Nervenarzt · 2023Review
- Article
- Subarachnoid hemorrhages and aneurysms during the SARS-CoV2-pandemia at a tertiary medical center - Analysis of incidence and outcome.Brain & spine · 2023Article
- Spontaneous intramedullary hematoma following COVID-19 vaccination: A case report.Clinical case reports · 2022Article
- Clinical and laboratory characteristics of children with neurological presentations of COVID-19: a single-center experience.Journal of medicine and life · 2022Article
- Neurologic manifestations of COVID-19 in critically ill patients: results of the prospective multicenter registry PANDEMIC.Critical care (London, England) · 2022Observational
- SARS-CoV2 Infection and Comorbidities, Role in Oncogenesis.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- [Rare encephalitis after vaccination against SARS-CoV-2].Der Nervenarzt · 2022Article
- Article
- SARS-COV-2 - the pandemic of the XXI century, clinical manifestations - neurological implications.Journal of medicine and life · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious neurological manifestations of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported, associated with a broad spectrum of diverse neurological symptoms and syndromes. Estimating rate and relevance of these manifestations remains difficult as there is a lack of standardised case definitions.
methodsWe defined comprehensive categories including most reported neurological manifestations associated with SARS-CoV-2 to allow for a more standardised data collection. After a literature search of MEDLINE with ten keywords, 12 selected studies and larger case series were included. We compared the rate and relevance of neurological manifestations in hospitalized patients. We propose four main categories including 1) cerebrovascular disease, 2) inflammatory syndromes of the central nervous system (CNS), peripheral nervous system (PNS) and muscle, 3) metabolic/toxic dysfunction of CNS, PNS and muscle and 4) miscellaneous disorders.
conclusionAgeusia (702) and anosmia (805) have been reported as the most common and the first occurring neurological symptoms. Cerebrovascular disease (451) and encephalopathy (663) were associated with a more severe course and worse clinical outcome. Any neurological manifestation was associated with a longer hospital stay and a higher morbidity and mortality compared to patients without neurological manifestations. We suggest reporting future neurological manifestations of coronavirus disease-19 (COVID-19) following a pathophysiology-based approach using standardized pre-defined case definitions to yield more specific and comparable data.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.