ArticleThe Journal of international medical research2021
Periodontal disease as a predictor of chronic kidney disease (CKD) stage in older adults.
Article in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Oral Health in Early and Advanced Stages (1-4) of Chronic Kidney Disease: A Systematic Review and Meta-Analysis.International dental journal · 2026Pooled it
- Prevalence of hypertension and diabetes mellitus in Peruvian patients with chronic kidney disease: a systematic review and meta-analysis.BMC nephrology · 2024Pooled it
- Relationship between oral microbiota and chronic kidney disease: facts and perspectives.Journal of oral microbiology · 2026Review
- Oral health-related quality of life among chronic kidney disease patients across disease stages: A comparative analysis.Bioinformation · 2026Article
- Exploring the association of calbindin -D28K in renal dialysis with oral health: a comprehensive review.Frontiers in oral health · 2025Review
- The Molecular Comorbidity Network of Periodontal Disease.International journal of molecular sciences · 2024Article
- Behind the Smile: Detecting Chronic Kidney Disease Through Oral Health Screenings.Hawai'i journal of health & social welfare · 2024Article
- Interaction of periodontal clinical indicators in metabolic syndrome and nonalcoholic fatty liver disease: Implications for preventive interventions.The Saudi dental journal · 2024Article
- Investigating the causal relationship between human blood/urine metabolites and periodontal disease using two-sample Mendelian randomization.Health science reports · 2024Article
- Oral Health and Oral Health-Related Quality of Life in Patients with Primary Sjögren's Syndrome.Medicina (Kaunas, Lithuania) · 2023Observational
- Chronic Kidney Disease and Periodontitis Interplay-A Narrative Review.International journal of environmental research and public health · 2023Review
- Oral Lesions Associated with COVID-19 and the Participation of the Buccal Cavity as a Key Player for Establishment of Immunity against SARS-CoV-2.International journal of environmental research and public health · 2022Review
- Oral health-related quality of life in chronic kidney disease patients.Dental research journal · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to evaluate periodontal disease as a predictor of chronic kidney disease (CKD) stage in older adults.
methodsA total of 1159 adults aged 65 to 80 years and diagnosed with periodontal disease and CKD (stages 1, 2, and 3) were randomly selected for a cross-sectional study. Periodontal status was assessed using the Community Periodontal Index of Treatment Needs (CPITN) and CKD was staged using the National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF-KDOQI) guidelines.
resultsIn patients with stage 1 CKD, the odds ratios (ORs) (95% confidence intervals [CIs]) for CPITN-1, CPITN-2, CPITN-3, and CPITN-4 were 1.13 (0.83-1.55), 1.47 (1.13-1.81), 1, and 1, respectively. In patients with stage 2 CKD, the ORs (95% CIs) for CPITN-1, CPITN-2, CPITN-3, and CPITN-4 were 1.49 (1.14-1.93), 1.37 (1.02-1.78), 3.07 (2.81-3.25), and 3.65 (3.49-3.71), respectively. In patients with stage 3 CKD, the ORs (95% CIs) for CPITN-1, CPITN-2, CPITN-3, and CPITN-4 were 1, 1, 4.61 (4.47-5.21), and 5.23 (5.14-5.47), respectively.
conclusionThe highest CPITN values (CPITN-3 and CPITN-4) were associated with CKD stages 2 and 3. Thus, periodontal disease may be associated with progression of CKD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.