Evidence map›Paper›PMID 34311585›Full record

ArticlemBio2021

Role of Premycofactocin Synthase in Growth, Microaerophilic Adaptation, and Metabolism of Mycobacterium tuberculosis.

Gopinath Krishnamoorthy, Peggy Kaiser, Patricia Constant, Ulrike Abu Abed, Monika Schmid, Christian K Frese, Volker Brinkmann, Mamadou Daffé, Stefan H E Kaufmann

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Exposure ofFrontiers in tuberculosis · 2024
    Article
  7. Article
  8. ACS chemical biology · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Gopinath KrishnamoorthyDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Peggy KaiserDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Patricia ConstantDépartement Tuberculose & Biologie des Infections, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France.
Ulrike Abu AbedCore Facility Microscopy, Max Planck Institute for Infection Biology, Berlin, Germany.
Monika SchmidCore Facility Proteomics, Max Planck Institute for Infection Biology, Berlin, Germany.
Christian K FreseMax-Planck-Unit for the Science of Pathogens, Berlin, Germany.
Volker BrinkmannCore Facility Microscopy, Max Planck Institute for Infection Biology, Berlin, Germany.
Mamadou DafféDépartement Tuberculose & Biologie des Infections, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France.
Stefan H E KaufmannDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Max Planck Institute for Infection Biology · DECentre National de la Recherche Scientifique · FRInstitute for Advanced Study · USMax Planck Unit for the Science of Pathogens · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycofactocin is a new class of peptide-derived redox cofactors present in a selected group of bacteria including Mycobacterium tuberculosis. Mycofactocin biosynthesis requires at least six genes, including

Indexed as

Adaptation, PhysiologicalAnaerobiosisAnimalsBacterial ProteinsBiosynthetic PathwaysFemaleGene Expression Regulation, BacterialMaleMiceMice, Inbred C57BLMycobacterium tuberculosisPeptidesBacterial ProteinsPeptidesglucose metabolismhypoxialactate metabolismMycobacterium tuberculosismycofactocinprotein aggregationredox cofactor

Identifiers

PMID34311585
PMCPMC8406134
OpenAlexW3185514526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.