Evidence map›Paper›PMID 34311384›Full record

ReviewCurrent opinion in genetics & development2021

Mitotic recombination in yeast: what we know and what we don't know.

Sue Jinks-Robertson, Thomas D Petes

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Detection of "hidden" mitotic crossovers by long-read DNA sequencing.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. bioRxiv : the preprint server for biology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Practical Approaches for the YeastInternational journal of molecular sciences · 2023
    Review
  11. Article
  12. Article
  13. Global genomic instability caused by reduced expression of DNA polymerase ε in yeast.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sue Jinks-RobertsonDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, United States.
Thomas D PetesDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, United States. Electronic address: tom.petes@duke.edu.
Duke University · US

Funding

Genetic regulation of genome stability in yeastR35GM118020 · NIGMS · DUKE UNIVERSITY · PI PETES, THOMAS · 2016 to 2025
$7.0M
Regulation of mitotic genome stability in yeast.R35GM118077 · NIGMS · DUKE UNIVERSITY · PI JINKS-ROBERTSON, SUE · 2016 to 2023
$4.5M
NIGMS NIH HHS R35 GM118020NIGMS NIH HHS R35 GM118077
6 · The paper itself

Abstract

Saccharomyces cerevisiae is at the forefront of defining the major recombination mechanisms/models that repair targeted double-strand breaks during mitosis. Each of these models predicts specific molecular intermediates as well as genetic outcomes. Recent use of single-nucleotide polymorphisms to track the exchange of sequences in recombination products has provided an unprecedented level of detail about the corresponding intermediates and the extents to which different mechanisms are utilized. This approach also has revealed complexities that are not predicted by canonical models, suggesting that modifications to these models are needed. Current data are consistent with the initiation of most inter-homolog spontaneous mitotic recombination events by a double-strand break. In addition, the sister chromatid is preferred over the homolog as a repair template.

Indexed as

DNA Breaks, Double-StrandedSaccharomyces cerevisiaeDNA RepairMitosisSister Chromatid Exchange

Identifiers

PMID34311384
PMCPMC8671248
OpenAlexW3185835314

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.