Evidence map›Paper›PMID 34310294›Full record

ArticleIEEE transactions on medical imaging2021

Multi-Band Brain Network Analysis for Functional Neuroimaging Biomarker Identification.

Rongyao Hu, Ziwen Peng, Xiaofeng Zhu, Jiangzhang Gan, Yonghua Zhu, Junbo Ma, Guorong Wu

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Rongyao Hu
Ziwen Peng
Xiaofeng Zhu
Jiangzhang Gan
Yonghua Zhu
Junbo Ma
Guorong Wu
University of Electronic Science and Technology of China · CNUniversity of North Carolina at Chapel Hill · USSouth China Normal University · CN

Funding

Understanding Selectivity Mechanisms of Network Vulnerability and Resilience in Alzheimer's Disease by Establishing a Neurobiological Basis through Network NeuroscienceRF1AG068399 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2020 to 2020
$1.9M
Understanding Selectivity Mechanisms of Network Vulnerability and Resilience in Alzheimer's Disease by Establishing a Neurobiological Basis through Network NeuroscienceR01AG068399 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2024 to 2024
$481k
Longitudinal Analysis for Early Diagnosis of Alzheimer's DiseaseK01AG049089 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2016 to 2019
$478k
Longitudinal Analysis of the Dynamic Network Disruptions in Alzheimer's DiseaseR21AG059065 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STYNER, MARTIN ANDREAS, WU, GUORONG · 2018 to 2019
$428k
Uncovering the Heterogeneity of Neurodegeneration Trajectories in Alzheimer's Disease Using a Network Guided Reaction-Diffusion ModelR03AG073927 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2021 to 2022
$317k
Continuing Tool Development for Longitudinal Network Analysis: Enriching the Diagnostic Power of Disease-Specific Connectomic Biomarkers by Deep Graph LearningR03AG070701 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2021 to 2022
$303k
NIA NIH HHS K01 AG049089NIA NIH HHS R01 AG068399NIA NIH HHS R03 AG070701NIA NIH HHS R03 AG073927NIA NIH HHS R21 AG059065NIA NIH HHS RF1 AG068399
6 · The paper itself

Abstract

The functional connectomic profile is one of the non-invasive imaging biomarkers in the computer-assisted diagnostic system for many neuro-diseases. However, the diagnostic power of functional connectivity is challenged by mixed frequency-specific neuronal oscillations in the brain, which makes the single Functional Connectivity Network (FCN) often underpowered to capture the disease-related functional patterns. To address this challenge, we propose a novel functional connectivity analysis framework to conduct joint feature learning and personalized disease diagnosis, in a semi-supervised manner, aiming at focusing on putative multi-band functional connectivity biomarkers from functional neuroimaging data. Specifically, we first decompose the Blood Oxygenation Level Dependent (BOLD) signals into multiple frequency bands by the discrete wavelet transform, and then cast the alignment of all fully-connected FCNs derived from multiple frequency bands into a parameter-free multi-band fusion model. The proposed fusion model fuses all fully-connected FCNs to obtain a sparsely-connected FCN (sparse FCN for short) for each individual subject, as well as lets each sparse FCN be close to its neighbored sparse FCNs and be far away from its furthest sparse FCNs. Furthermore, we employ the l

Indexed as

Alzheimer DiseaseConnectomeBiomarkersBrainHumansMagnetic Resonance ImagingNeuroimagingBiomarkers

Identifiers

PMID34310294
PMCPMC8931676
OpenAlexW3184812167

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.