Evidence map›Paper›PMID 34310160›Full record

ArticleCirculation2021

Cardiac Cell Therapy Fails to Rejuvenate the Chronically Scarred Rodent Heart.

Ronald J Vagnozzi, Rajesh K Kasam, Michelle A Sargent, Jeffery D Molkentin

Abstract readLetter
In one paragraph

Article in Circulation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. [Diagnostics (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Rejuvenating the Aging Heart by Enhancing the Expression of theInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Ronald J VagnozziDepartment of Pediatrics, University of Cincinnati (R.J.V., R.K.K., M.A.S., J.D.M.), Cincinnati Children's Hospital Medical Center, OH.
Rajesh K KasamDepartment of Pediatrics, University of Cincinnati (R.J.V., R.K.K., M.A.S., J.D.M.), Cincinnati Children's Hospital Medical Center, OH.
Michelle A SargentDepartment of Pediatrics, University of Cincinnati (R.J.V., R.K.K., M.A.S., J.D.M.), Cincinnati Children's Hospital Medical Center, OH.
Jeffery D MolkentinDepartment of Pediatrics, University of Cincinnati (R.J.V., R.K.K., M.A.S., J.D.M.), Cincinnati Children's Hospital Medical Center, OH.

Funding

MOLECULAR PATHWAYS CONTROLLING CARDIAC GENE EXPRESSIONR01HL060562 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI MOLKENTIN, JEFFERY D · 1998 to 2021
$4.1M
Howard Hughes Medical InstituteNHLBI NIH HHS R01 HL060562
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Stem Cell TransplantationAnimalsBone Marrow CellsBone Marrow TransplantationCardiomyopathy, RestrictiveCell- and Tissue-Based TherapyChronic DiseaseDisease Models, AnimalFemaleFibrosisIschemiaMaleMiceRodentiaTreatment FailureTreatment Outcomecell- and tissue-based therapymodels, animalmyocardial infarctionstem cells

Identifiers

PMID34310160
PMCPMC8323965

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.