Evidence map›Paper›PMID 34309630›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022

Reuniting the Body "Neck Up and Neck Down" to Understand Cognitive Aging: The Nexus of Geroscience and Neuroscience.

Abbi R Hernandez, Jessica M Hoffman, Caesar M Hernandez, Constanza J Cortes, Patricia Jumbo-Lucioni, Mark G Baxter, Karyn A Esser, Andrew C Liu, Lori L McMahon, Jennifer L Bizon and 3 more

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Cognitive reserve and everyday functioning in cognitively unimpaired older adults: evidence from the CAN-PROTECT study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. A Neuroscience Primer for Integrating Geroscience With the Neurobiology of Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  6. Bridging the Gap: A Geroscience Primer for Neuroscientists With Potential Collaborative Applications.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Abbi R HernandezDivision of Gerontology, Geriatrics and Palliative Care, School of Medicine, University of Alabama at Birmingham, USA.ORCID 0000-0002-3855-4047
Jessica M HoffmanDepartment of Biology, University of Alabama at Birmingham, USA.
Caesar M HernandezDepartment of Cellular, Development, and Integrative Biology, School of Medicine, University of Alabama at Birmingham, USA.ORCID 0000-0001-9690-5119
Constanza J CortesUAB Center for Exercise Medicine, University of Alabama at Birmingham, USA.ORCID 0000-0002-6033-7428
Patricia Jumbo-LucioniDepartment of Biology, University of Alabama at Birmingham, USA.ORCID 0000-0002-9329-0873
Mark G BaxterNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Karyn A EsserDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, Gainesville, USA.
Andrew C LiuDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, Gainesville, USA.
Lori L McMahonUAB Center for Exercise Medicine, University of Alabama at Birmingham, USA.
Jennifer L BizonDepartment of Neuroscience and Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida College of Medicine, Gainesville, USA.
Sara N BurkeDepartment of Neuroscience and Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida College of Medicine, Gainesville, USA.
Thomas W BufordDivision of Gerontology, Geriatrics and Palliative Care, School of Medicine, University of Alabama at Birmingham, USA.
Christy S CarterDivision of Gerontology, Geriatrics and Palliative Care, School of Medicine, University of Alabama at Birmingham, USA.ORCID 0000-0001-9657-3193

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
Sex hormones and arthritis in a long lived animal modelP30AG050886 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jianhua Zhang · 2015 to 2026
$11.3M
Molecular, Cellular and Physiological Mechanisms of the Mammalian Circadian ClockR01NS054794 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI HOGENESCH, JOHN B, LIU, ANDREW C. · 2007 to 2022
$8.1M
Interdisciplinary Training in Pathobiology and Rehabilitation Medicine.T32HD071866 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JAMES RIMMER, Anna E. Thalacker-Mercer · 2012 to 2026
$4.8M
UF PASS: Regulation of exercise transducers: supplement for diverse studentsU01AG055137 · NIA · UNIVERSITY OF FLORIDA · PI ESSER, KARYN A · 2017 to 2023
$3.2M
Consequences of Noradrenergic Degeneration in the Novel TgF344-AD Rat ModelR01AG066489 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MCMAHON, LORI LYNN · 2020 to 2024
$2.9M
Enhanced skeletal muscle proteostasis as a determinant of CNS protein quality control and neural function in the aging brainRF1AG057264 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CORTES, CONSTANZA JAVIERA, LA SPADA, ALBERT R · 2017 to 2021
$2.7M
Circadian clock regulation of myocardial ion channel expression and functionR01HL153042 · NHLBI · UNIVERSITY OF FLORIDA · PI DELISLE, BRIAN P, ESSER, KARYN A · 2020 to 2023
$2.6M
Metabolic Interventions for Enhancing Cognitive Resilience in Aging and Alzheimers DiseaseRF1AG060977 · NIA · UNIVERSITY OF FLORIDA · PI BURKE, SARA N · 2019 to 2019
$1.9M
The metabolomic consequences of small size and long lifeR00AG059920 · NIA · AUGUSTA UNIVERSITY · PI HOFFMAN, JESSICA MARIE · 2022 to 2024
$742k
Interconnections among Cognition, Pain, and Physical Function in Aging.K02AG062498 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BUFORD, THOMAS W · 2020 to 2024
$524k
The metabolomic consequences of small size and long lifeK99AG059920 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HOFFMAN, JESSICA MARIE · 2019 to 2021
$342k
NHLBI NIH HHS R01 HL153042NIA NIH HHS K02 AG062498NIA NIH HHS K99 AG059920NIA NIH HHS P30 AG028740NIA NIH HHS P30 AG050886NIA NIH HHS R00 AG059920NIA NIH HHS R01 AG066489NIA NIH HHS R03 AG063215NIA NIH HHS RF1 AG057264NIA NIH HHS RF1 AG060977NIA NIH HHS U01 AG055137NICHD NIH HHSNIH HHS T32HD071866NINDS NIH HHS R01 NS054794
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cognitive AgingGeroscienceLongevityBrain agingCognitive declineMetabolismMuscles

Identifiers

PMID34309630
PMCPMC8751793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.