Evidence map›Paper›PMID 34309400›Full record

ArticleJournal of bacteriology2021

The Deletion of

Xudong Wang, Xinguang Lin, Zhixin Wan, Shaohui Wang, Jiakun Zuo, Zhihao Wang, Yuanyuan Xu, Xiangan Han, Jinfeng Miao

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xudong Wang *MOE Joint International Research Laboratory of Animal Health and Food Safety, Key Laboratory of Animal Physiology & Biochemistry, College of Veterinary Medicine, Nanjing Agricultural Universitygrid.27871.3b, Nanjing, China.
Xinguang Lin *MOE Joint International Research Laboratory of Animal Health and Food Safety, Key Laboratory of Animal Physiology & Biochemistry, College of Veterinary Medicine, Nanjing Agricultural Universitygrid.27871.3b, Nanjing, China.
Zhixin WanMOE Joint International Research Laboratory of Animal Health and Food Safety, Key Laboratory of Animal Physiology & Biochemistry, College of Veterinary Medicine, Nanjing Agricultural Universitygrid.27871.3b, Nanjing, China.
Shaohui WangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Jiakun ZuoMOE Joint International Research Laboratory of Animal Health and Food Safety, Key Laboratory of Animal Physiology & Biochemistry, College of Veterinary Medicine, Nanjing Agricultural Universitygrid.27871.3b, Nanjing, China.
Zhihao WangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Yuanyuan XuMOE Joint International Research Laboratory of Animal Health and Food Safety, Key Laboratory of Animal Physiology & Biochemistry, College of Veterinary Medicine, Nanjing Agricultural Universitygrid.27871.3b, Nanjing, China.
Xiangan HanShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Jinfeng MiaoMOE Joint International Research Laboratory of Animal Health and Food Safety, Key Laboratory of Animal Physiology & Biochemistry, College of Veterinary Medicine, Nanjing Agricultural Universitygrid.27871.3b, Nanjing, China.ORCID 0000-0001-6229-3767
Nanjing Agricultural University · CNShanghai Veterinary Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammary gland-derived Escherichia coli is an important pathogen causing dairy cow mastitis. Mammary gland mucosal immunity against infectious E. coli mainly depends on recognition of pathogen-associated molecular patterns by innate receptors. Stimulator of interferon (IFN) gene (STING) has recently been the dominant mediator in reacting to bacterial intrusion and preventing inflammatory disorders. In this study, we first proved that the diguanylate cyclase YeaJ relieves mouse mammary gland pathological damage by changing E. coli phenotypic and host STING-dependent innate immunity responses. YeaJ decreases mammary gland circular vacuoles, bleeding, and degeneration in mice. In addition, YeaJ participates in STING-IRF3 signaling to regulate inflammation

Indexed as

AnimalsBiofilmsCell AdhesionEpithelial CellsEscherichia coliEscherichia coli ProteinsFemaleGene Expression Regulation, BacterialMacrophagesMammary Glands, AnimalMiceMovementMutationPhosphorus-Oxygen LyasesRAW 264.7 CellsEscherichia coli ProteinsPhosphorus-Oxygen LyasesyeaJ protein, E colibiological characteristicsSTING-IRF3 signaling pathwayYeaJ

Identifiers

PMID34309400
PMCPMC8459762
OpenAlexW3184758158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.