Evidence map›Paper›PMID 34309397›Full record

ArticleJournal of bacteriology2021

Type II Fatty Acid Synthesis Pathway and Cyclopropane Ring Formation Are Dispensable during Enterococcus faecalis Systemic Infection.

Constantin Hays, Clara Lambert, Sophie Brinster, Gilles Lamberet, Laurence du Merle, Karine Gloux, Alexandra Gruss, Claire Poyart, Agnes Fouet

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Two putativeMicrobiology (Reading, England) · 2025
    Article
  5. Microbiology (Reading, England) · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Acyl-AcpB, a FabT corepressor inJournal of bacteriology · 2023
    Article
  11. Article
  12. Review
  13. Review
  14. TheFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Constantin HaysUniversité de Paris, Institut Cochingrid.462098.1, INSERM, CNRS, Paris, France.
Clara LambertUniversité de Paris, Institut Cochingrid.462098.1, INSERM, CNRS, Paris, France.
Sophie BrinsterUniversité de Paris, Institut Cochingrid.462098.1, INSERM, CNRS, Paris, France.
Gilles LamberetMICALIS, UMR1319, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Domaine de Vilvert, Jouy en Josas, France.
Laurence du MerleInstitut Pasteurgrid.428999.7, Unité de Biologie des Bactéries Pathogènes à Gram Positif, Paris, France.
Karine GlouxMICALIS, UMR1319, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Domaine de Vilvert, Jouy en Josas, France.
Alexandra GrussMICALIS, UMR1319, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Domaine de Vilvert, Jouy en Josas, France.ORCID 0000-0001-7426-5229
Claire Poyart *Université de Paris, Institut Cochingrid.462098.1, INSERM, CNRS, Paris, France.
Agnes Fouet *Université de Paris, Institut Cochingrid.462098.1, INSERM, CNRS, Paris, France.ORCID 0000-0001-7715-9157
Centre National de la Recherche Scientifique · FRMicrobiologie de l’alimentation au service de la santé · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterococcus faecalis, a multiple antibiotic-resistant Gram-positive bacterium, has emerged as a serious nosocomial pathogen. Here, we used a genetic approach to characterize the strategies used by E. faecalis to fulfill its requirements for endogenous fatty acid (FA) synthesis

Indexed as

AnimalsBacterial ProteinsCulture MediaCyclopropanesDNA, BacterialEnterococcus faecalisFatty AcidsFemaleGene Expression Regulation, BacterialGene Expression Regulation, EnzymologicHumansMethyltransferasesMiceMice, Inbred BALB CSerumBacterial ProteinsCulture MediacyclopropaneCyclopropanescyclopropane synthetaseDNA, BacterialFatty AcidsMethyltransferasesantibiotic targetcyclopropane ring formationEnterococcus faecalisFASII pathwayfatty acidssepticemic infection

Identifiers

PMID34309397
PMCPMC8459760
OpenAlexW3184212925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.