Evidence map›Paper›PMID 34309372›Full record

ArticleACS chemical biology2021

Development of an Acrylamide-Based Inhibitor of Protein

Saara-Anne Azizi, Tong Lan, Clémence Delalande, Rahul S Kathayat, Fernando Banales Mejia, Alice Qin, Noah Brookes, Perla Jasmine Sandoval, Bryan C Dickinson

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
  2. Article
  3. Biochemistry · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. The Roles of ProteinCancer communications (London, England) · 2026
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Recent Overview of Protein Palmitoylation and Profiling Methodologies.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Saara-Anne AziziDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-9226-9917
Tong LanDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0003-3923-5408
Clémence DelalandeDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Rahul S KathayatDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-9159-2413
Fernando Banales MejiaDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Alice QinDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Noah BrookesDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Perla Jasmine SandovalDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Bryan C DickinsonDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-9616-1911
University of Chicago · US

Funding

MEDICAL SCIENTIST TRAININGT32GM007281 · NIGMS · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 1985 to 2022
$32.1M
UNIVERSITY OF CHICAGO PREPR25GM066522 · NIGMS · UNIVERSITY OF CHICAGO · PI CARRILLO, ROBERT ARNULFO, RANDALL, GLENN C · 2004 to 2024
$6.7M
Rapid selection approaches to understand and reprogram proteins and peptidesR35GM119840 · NIGMS · UNIVERSITY OF CHICAGO · PI Bryan Dickinson · 2016 to 2026
$4.8M
Acquisition of a Q-Exactive HF Mass SpectrometerS10OD027016 · OD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI COLOGNA, STEPHANIE M · 2019 to 2019
$600k
Identifying the mechanisms and biological impact of ERK lipidation in metabolic signalingF30DK125088 · NIDDK · UNIVERSITY OF CHICAGO · PI AZIZI, SAARA-ANNE · 2020 to 2022
$153k
NIDDK NIH HHS F30 DK125088NIGMS NIH HHS R25 GM066522NIGMS NIH HHS R35 GM119840NIGMS NIH HHS T32 GM007281NIH HHS S10 OD027016
6 · The paper itself

Abstract

Protein

Indexed as

AcrylamidesAcylationAcyltransferasesAnimalsCD36 AntigensCell Line, TumorEnzyme InhibitorsErbB ReceptorsHumansLipoylationMiceProtein Processing, Post-TranslationalAcrylamidesAcyltransferasesCD36 AntigensCd36 protein, mouseEGFR protein, humanEnzyme InhibitorsErbB ReceptorsZDHHC20 protein, human

Identifiers

PMID34309372
PMCPMC8590885
OpenAlexW3170317559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.