Evidence map›Paper›PMID 34309034›Full record

ArticleJournal of food science2021

Development of a direct competitive enzyme-linked immunosorbent assay for quantitation of sodium saccharin residue in food.

Yajie Zhao, Mian Wang, Man Zhang, Xiaolin Yang, ZhenFeng Li, Natalia Vasylieva, Guiyu Tan, Baomin Wang, Bruce D Hammock

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of food science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yajie ZhaoCollege of Agriculture and Biotechnology, China Agricultural University, Beijing, China.
Mian WangCollege of Agriculture and Biotechnology, China Agricultural University, Beijing, China.
Man ZhangCollege of Agriculture and Biotechnology, China Agricultural University, Beijing, China.
Xiaolin YangCollege of Agriculture and Biotechnology, China Agricultural University, Beijing, China.
ZhenFeng LiCollege of Agriculture and Biotechnology, China Agricultural University, Beijing, China.
Natalia VasylievaDepartment of Entomology and UCD Comprehensive Cancer Center, University of California, Davis, California, USA.
Guiyu TanCollege of Agriculture and Biotechnology, China Agricultural University, Beijing, China.
Baomin WangCollege of Agriculture and Biotechnology, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0002-4235-198X
Bruce D HammockDepartment of Entomology and UCD Comprehensive Cancer Center, University of California, Davis, California, USA.
China Agricultural University · CNUniversity of California, Davis · US

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1987 to 2021
$50.1M
NIEHS NIH HHS P42 ES004699
6 · The paper itself

Abstract

Sodium saccharin is a common artificial sweetener. However, due to its possible carcinogenic effects and causing metabolic disorders, many countries have strictly regulated its use in food. In the study, we prepared a specific monoclonal antibody (mAb 2H11) using the new hapten (6-carboxylsaccharin) and developed a direct competitive enzyme-linked immunosorbent assay (dcELISA) for the screening of sodium saccharin residue in food. The half-maximum inhibition concentration (IC

Indexed as

Food ContaminationSaccharinChromatography, LiquidEnzyme-Linked Immunosorbent AssaySodiumTandem Mass SpectrometrySaccharinSodiumdcELISAfood additivesmAbsodium saccharin

Identifiers

PMID34309034
PMCPMC9514150
OpenAlexW3184680428

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.