ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021
[Association of number and quality of embryos transferred with early pregnancy loss in infertile women at an advanced age undergoing frozen-thawed embryo transfer].
Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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7 authors at 2 institutions in 1 country.
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Abstract
objectiveTo investigate the association of the number and quality of embryos transferred in frozen-thawed embryo transfer (FET) cycle with the occurrence of early pregnancy loss in infertile women at an advanced age.
methodsWe collected the data of a total of 2622 infertile women aged 36 years or older receiving FET between January, 2015 and December, 2018. The occurrence of early pregnancy loss was analyzed in these women, and the relation of age, the number and quality of embryos transferred with early pregnancy loss was explored in the overall cohort and in different age (36-37, 38-39, 40, 41, 42, 43, 44 and 45-48 years) groups.
resultsOf the 2622 women, 976 (37.2%) achieved clinical pregnancy after FET, among whom 241 (24.7%) experienced early pregnancy loss. The clinical pregnancy rate and live birth rate decreased significantly and early pregnancy loss rate increased markedly with age (
conclusionsIn infertile women at an advanced age, the early pregnancy loss rate in FET cycle increases with age. An advanced age is an inherent risk factor for early pregnancy loss, therefore ART should be implemented as soon as possible for these women. To reduce early pregnancy loss rate and balance the risk of multiple pregnancies, the number of embryos transferred should be carefully determined on the basis of embryo quality.
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